Abstract
9-Methylsulfanyl pyridine-stretched adenine and hypoxanthine
derivatives have been prepared via regioselective reaction of a
5-aminoimidazole with 2-(bis-methylsulfanylmethylene)malononitrile [(NC)2 C=C(SMe)2 ].
The 9-methylsulfanyl substituent can be replaced by sequential oxidation
and substitution by nucleophiles including amines.
Key words
5-aminoimidazoles -
lin -pyridoadenines - soft electrophiles - tricyclic heterocycles - pyridine-stretched
purines
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