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Synfacts 2008(12): 1284-1284  
DOI: 10.1055/s-0028-1087302
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

A Full-Color-Tunable Fluorophore

Contributor(s): Timothy M. Swager, Fei Wang
E. Kim, M. Koh, J. Ryu, S. B. Park*
Seoul National University, Korea
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Publication History

Publication Date:
20 November 2008 (online)

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Significance

A novel full-color-tunable fluorophore, 1,2-dihydropyrrolo[3,4-β]indolizin-3-one is reported, which was synthesized via 1,3-dipolar cycloaddition and oxidative aromatization. The emission maxima can be tuned by using different substitution groups. The bioapplications of some of these fluorophores were demonstrated by immunofluorescence.