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Synlett 2008(18): 2811-2814
DOI: 10.1055/s-0028-1083548
DOI: 10.1055/s-0028-1083548
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New YorkAlternative I-D Exchange Reaction on Pyrimidine and Purine Nuclei Mediated by Tributyltin Hydride Using THF-d 8 as a Deuterium Source
Further Information
Received
2 July 2008
Publication Date:
15 October 2008 (online)
Publication History
Publication Date:
15 October 2008 (online)

Abstract
A method for the regioselective deuteration of pyrimidine and purine rings mediated by Bu3SnH using THF-d 8 as a deuterium source on the basis of a radical reaction was developed.
Key words
regioselective deuteration - pyrimidine - purine - THF-d 8 - tributyltin hydride
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