A Chemoselective, Easy Bromination of (Hydroxymethyl)phenols

Abstract

A simple and chemoselective method for direct bromination of (hydroxymethyl)phenols via reaction with 2,4,6-trichloro[1,3,5]triazine in N,N-dimethylformamide at room temperature is described. The reaction occurs without affecting the phenolic hydroxy group.

(hydroxymethyl)phenols - cyanuric acid - (bromomethyl)phenols - bromination - chemoselectivity

References

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