A Photochemical Cyclization of Glyoxalates via an Internally Directed C–H Insertion

Abstract

An unusual photochemical cyclization of glyoxylate esters has been described resulting in selective formation of an eight-membered lactone. Site-selective hydrogen abstraction leads to a novel C–H remote functionalization.

Keywords

Photolysis - C–H insertion - Glyoxylate - Cyclizations - Remote functionalization - Internally directed reactions

Publikationsverlauf

Eingereicht: 10. September 2025

Angenommen nach Revision: 16. Oktober 2025

Artikel online veröffentlicht:
17. November 2025

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