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DOI: 10.1055/a-2693-0944
Step-Off Between the Lateral Femoral Condyle and the Lateral Tibial Plateau: Association with Degenerative Lateral Meniscal Tears and Lateral Osteoarthritis of the Knee
Authors

Abstract
A naturally occurring step-off (SO) between the lateral femoral condyle and the lateral tibial plateau creates a zone where the middle part of the lateral meniscus (LM) is not covered by the femoral condyle. We assessed the effects of this SO on the development of meniscal damage and osteoarthritis (OA). A total of 82 patients who underwent meniscectomy of the LM were retrospectively reviewed. The patients were divided into two groups based on findings of OA on radiography. The control group consisted of patients without OA who were matched to those who had acute isolated anterior cruciate ligament injuries. The size of the SO and extrusion of the LM were obtained by preoperative magnetic resonance imaging. The mean size of the SO in the LM group was significantly larger than that in the control group (4.0 ± 0.92 mm vs. 1.6 ± 1.11 mm, p < 0.0001). Extrusion of LM was not significantly different between the two groups. Extrusion of the tibial side in patients with OA was significantly larger than that in the non-OA group (1.9 ± 1.2 vs. 0.50 ± 0.95, p < 0.001). However, the size of the SO was not significantly different (4.2 ± 1.28 vs. 4.0 ± 0.92, p = 0.53). A large SO was identified as an anatomical risk factor for degenerative LM tears, leading to extrusion of LM and development of lateral knee OA.
Keywords
lateral meniscus tear - lateral femoral condyle - meniscal extrusion - lateral knee osteoarthritisEthical Approval
The study protocol was approved by the institutional review board at the Gunma Chuo Hospital (IRB No. 2018–35).
Publication History
Received: 30 June 2025
Accepted: 30 August 2025
Accepted Manuscript online:
01 September 2025
Article published online:
22 September 2025
© 2025. Thieme. All rights reserved.
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References
- 1 Levy IM, Torzilli PA, Warren RF. The effect of medial meniscectomy on anterior-posterior motion of the knee. J Bone Joint Surg Am 1982; 64 (06) 883-888
- 2 Walker PS, Erkman MJ. The role of the menisci in force transmission across the knee. Clin Orthop Relat Res 1975; (109) 184-192
- 3 Voloshin AS, Wosk J. Shock absorption of meniscectomized and painful knees: a comparative in vivo study. J Biomed Eng 1983; 5 (02) 157-161
- 4 Berthiaume MJ, Raynauld JP, Martel-Pelletier J. et al. Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis 2005; 64 (04) 556-563
- 5 Jones S, Caplan N, St Clair Gibson A, Kader N, Kader D. Interactions between severity and location of chondral lesions and meniscal tears found at arthroscopy. Knee Surg Sports Traumatol Arthrosc 2011; 19 (10) 1699-1703
- 6 Salata MJ, Gibbs AE, Sekiya JK. A systematic review of clinical outcomes in patients undergoing meniscectomy. Am J Sports Med 2010; 38 (09) 1907-1916
- 7 Chatain F, Adeleine P, Chambat P, Neyret P. Société Française d'Arthroscopie. A comparative study of medial versus lateral arthroscopic partial meniscectomy on stable knees: 10-year minimum follow-up. Arthroscopy 2003; 19 (08) 842-849
- 8 Ding C, Martel-Pelletier J, Pelletier JP. et al. Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume. Arthritis Res Ther 2007; 9 (02) R21
- 9 Badlani JT, Borrero C, Golla S, Harner CD, Irrgang JJ. Data from the Osteoarthritis Initiative. The effects of meniscus injury on the development of knee osteoarthritis: data from the osteoarthritis initiative. Am J Sports Med 2013; 41 (06) 1238-1244
- 10 Gale DR, Chaisson CE, Totterman SMC, Schwartz RK, Gale ME, Felson D. Meniscal subluxation: association with osteoarthritis and joint space narrowing. Osteoarthritis Cartilage 1999; 7 (06) 526-532
- 11 Emmanuel K, Quinn E, Niu J. et al. Quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis–data from the osteoarthritis initiative. Osteoarthritis Cartilage 2016; 24 (02) 262-269
- 12 Crema MD, Roemer FW, Felson DT. et al. Factors associated with meniscal extrusion in knees with or at risk for osteoarthritis: the multicenter osteoarthritis study. Radiology 2012; 264 (02) 494-503
- 13 Hunter DJ, Zhang YQ, Niu JB. et al. The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum 2006; 54 (03) 795-801
- 14 Svensson F, Felson DT, Zhang F. et al. Meniscal body extrusion and cartilage coverage in middle-aged and elderly without radiographic knee osteoarthritis. Eur Radiol 2019; 29 (04) 1848-1854
- 15 Zhang F, Kumm J, Svensson F, Turkiewicz A, Frobell R, Englund M. Risk factors for meniscal body extrusion on MRI in subjects free of radiographic knee osteoarthritis: longitudinal data from the osteoarthritis initiative. Osteoarthritis Cartilage 2016; 24 (05) 801-806
- 16 Verdonk P, Depaepe Y, Desmyter S. et al. Normal and transplanted lateral knee menisci: evaluation of extrusion using magnetic resonance imaging and ultrasound. Knee Surg Sports Traumatol Arthrosc 2004; 12 (05) 411-419
- 17 Khan N, McMahon P, Obaid H. Bony morphology of the knee and non-traumatic meniscal tears: is there a role for meniscal impingement?. Skeletal Radiol 2014; 43 (07) 955-962
- 18 Matsuda S, Miura H, Nagamine R. et al. Anatomical analysis of the femoral condyle in normal and osteoarthritic knees. J Orthop Res 2004; 22 (01) 104-109
- 19 Hatayama K, Terauchi M, Saito K, Hagiwara K, Higuchi H. Tibial tubercle in valgus osteoarthritic knees is more laterally positioned than in varus knees. J Arthroplasty 2016; 31 (10) 2303-2307
- 20 Costa CR, Morrison WB, Carrino JA. Medial meniscus extrusion on knee MRI: is extent associated with severity of degeneration or type of tear?. AJR Am J Roentgenol 2004; 183 (01) 17-23
- 21 Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957; 16 (04) 494-502
- 22 Snoeker BAM, Bakker EWP, Kegel CA, Lucas C. Risk factors for meniscal tears: a systematic review including meta-analysis. J Orthop Sports Phys Ther 2013; 43 (06) 352-367
- 23 Madan-Sharma R, Kloppenburg M, Kornaat PR. et al. Do MRI features at baseline predict radiographic joint space narrowing in the medial compartment of the osteoarthritic knee 2 years later?. Skeletal Radiol 2008; 37 (09) 805-811
- 24 Suganuma J. Lack of posteromedial tibiofemoral congruence at full flexion as a causative factor in isolated medial meniscal tears. J Orthop Sci 2002; 7 (02) 217-225
- 25 Habata T, Ishimura M, Ohgushi H, Tamai S, Fujisawa Y. Axial alignment of the lower limb in patients with isolated meniscal tear. J Orthop Sci 1998; 3 (02) 85-89
- 26 McGuire DA, Barber FA, Hendricks SD. Meniscal impingement syndrome. Arthroscopy 1996; 12 (06) 675-679
- 27 Dienst M, Greis PE, Ellis BJ, Bachus KN, Burks RT. Effect of lateral meniscal allograft sizing on contact mechanics of the lateral tibial plateau: an experimental study in human cadaveric knee joints. Am J Sports Med 2007; 35 (01) 34-42
- 28 Ahn JH, Kim K-II, Wang JH, Kyung BS, Seo MC, Lee SH. Arthroscopic repair of bucket-handle tears of the lateral meniscus. Knee Surg Sports Traumatol Arthrosc 2015; 23 (01) 205-210
- 29 Noble J, Hamblen DL. The pathology of the degenerate meniscus lesion. J Bone Joint Surg Br 1975; 57 (02) 180-186
- 30 Terauchi M, Hatayama K, Yanagisawa S, Saito K, Takagishi K. Sagittal alignment of the knee and its relationship to noncontact anterior cruciate ligament injuries. Am J Sports Med 2011; 39 (05) 1090-1094