Semin Respir Crit Care Med
DOI: 10.1055/a-2557-8463
Review Article

The Critical Role of Sleep in Enhancing Pulmonary Rehabilitation Outcomes

Mario Henríquez-Beltrán
1   Translational Research in Respiratory Medicine, Biomedical Research Institute of Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova-Santa Maria, Lleida, Spain
2   CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
3   Núcleo de Investigación en Ciencias de la Salud, Universidad Adventista de Chile, Chillán, Chile
4   Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Chile
,
Jessica González
1   Translational Research in Respiratory Medicine, Biomedical Research Institute of Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova-Santa Maria, Lleida, Spain
2   CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
,
Gonzalo Labarca
5   Departamento de Enfermedades Respiratorias, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
,
Adriano D.S. Targa
1   Translational Research in Respiratory Medicine, Biomedical Research Institute of Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova-Santa Maria, Lleida, Spain
2   CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain
› Author Affiliations

Funding The authors are supported by the Instituto de Salud Carlos III (ISCIII) through the projects PI22/00216 and COV20/00110, co-funded by European Union (Fondo Europeo de Desarrollo Regional-FEDER “Una manera de hacer Europa”), Centro de Investigación Biomédica en Red—Enfermedades Respiratorias (CIBERES), Donation Program “estar preparados” (UNESPA), Jané Mateu Foundation, and Sociedad Española de Neumología y Cirugía Torácica (SEPAR/1555–2024). Mario Henríquez-Beltrán and Adriano D.S. Targa have received financial support from Instituto de Salud Carlos III (PFIS 2023: FI23/00253 and Miguel Servet 2023: CP23/00095, respectively), co-funded by European Union (Fondo Social Europeo Plus, FSE + ).
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Abstract

Pulmonary rehabilitation is a comprehensive, interdisciplinary intervention that aims to enhance the physical and psychological well-being of individuals with chronic respiratory diseases. This approach entails the implementation of tailored therapies, including exercise training, education, and behavioral modification. Sleep plays a crucial role in numerous physiological processes, including the regulation of inflammation and tissue repair, both of which are fundamental to the efficacy of rehabilitation. A paucity of optimal sleep health has been associated with deleterious effects on pivotal factors that are indispensable for favorable outcomes in pulmonary rehabilitation, including mental and physical health and immune function. This, in turn, may increase susceptibility to impaired pulmonary function. The integration of pulmonary rehabilitation protocols with healthy sleep practices is expected to yield significant improvements in lung function and overall health, which will, in turn, promote long-term adherence to rehabilitative behaviors. This study aims to examine the relationship between sleep health and pulmonary rehabilitation outcomes.

Authors' Contributions

Study design: M.H.B., A.D.S.T. Data abstraction and collection: J.G., M.H.B. Initial draft: All authors. Review of the manuscript for important intellectual content: J.G., A.D.S.T., G.L. All authors have seen and approved the manuscript.




Publication History

Article published online:
31 March 2025

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