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DOI: 10.1055/a-2517-0803
Simultaneous Symmetrizing Surgery on the Contralateral Breast in Unilateral Autologous Breast Reconstruction Is Cost-Effective
Fundings None.
Abstract
Background Simultaneous symmetrizing surgery (SSS) at the time of unilateral free flap reconstruction has been described as a method to facilitate single-stage breast reconstruction. However, the impact on cost and number of additional procedures is not well described.
Methods Patients with unilateral free flap reconstruction were identified in national administrative data from 2017 to 2021 and followed for one year. Patients were stratified by immediate and delayed reconstruction, then further stratified into groups with and without SSS. Thirty-day complications included transfusion, wound dehiscence, surgical site infection, hematoma/seroma, and thromboembolism. The costs of initial hospitalization and subsequent surgeries were determined. Deferred symmetrizing surgeries within one year were identified. Chi-squared and Fisher exact tests and Wilcoxon tests were used for statistical analysis.
Results A total of 1,136 patients were identified, out of which 638 were delayed reconstructions: 75 with SSS and 563 without. There were no significant differences in patient characteristics or 30-day complications. Within one year of index reconstruction, fewer patients with SSS underwent revision surgery (29% vs. 51%, [p = 0.001]) or at least one additional procedure (36% vs. 57%, p < 0.001). Patients with SSS had lower total costs ($35,897 vs. $50,521, p = 0.005). There were 498 immediate reconstructions: 63 with SSS and 435 without. There were no significant differences in patient characteristics, 30-day complications, subsequent surgeries, or total costs.
Conclusion Symmetrizing procedures at the time of unilateral reconstruction may decrease the cost and number of subsequent surgeries without increasing complications.
Publikationsverlauf
Eingereicht: 03. Oktober 2024
Angenommen: 30. Dezember 2024
Accepted Manuscript online:
16. Januar 2025
Artikel online veröffentlicht:
10. Februar 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
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References
- 1 Alderman AK, Wilkins EG, Lowery JC, Kim M, Davis JA. Determinants of patient satisfaction in postmastectomy breast reconstruction. Plast Reconstr Surg 2000; 106 (04) 769-776
- 2 Yueh JH, Slavin SA, Adesiyun T. et al. Patient satisfaction in postmastectomy breast reconstruction: a comparative evaluation of DIEP, TRAM, latissimus flap, and implant techniques. Plast Reconstr Surg 2010; 125 (06) 1585-1595
- 3 Teo I, Reece GP, Huang SC. et al. Body image dissatisfaction in patients undergoing breast reconstruction: examining the roles of breast symmetry and appearance investment. Psychooncology 2018; 27 (03) 857-863
- 4 Losken A, Carlson GW, Bostwick III J, Jones GE, Culbertson JH, Schoemann M. Trends in unilateral breast reconstruction and management of the contralateral breast: the Emory experience. Plast Reconstr Surg 2002; 110 (01) 89-97
- 5 Smith JM, Boukovalas S, Chang EI. et al. Analysis of breast aesthetic revision procedures after unilateral abdominal-based free-flap breast reconstruction: a single-center experience with 1251 patients. Plast Reconstr Surg Glob Open 2023; 11 (03) e4861
- 6 Nahabedian MY. Managing the opposite breast: contralateral symmetry procedures. Cancer J 2008; 14 (04) 258-263
- 7 Chang EI, Lamaris G, Chang DW. Simultaneous contralateral reduction mammoplasty or mastopexy during unilateral free flap breast reconstruction. Ann Plast Surg 2013; 71 (02) 144-148
- 8 Pauchot J, Feuvrier D, Panouillères M, Pluvy I, Tropet Y. Benefit of simultaneous contralateral breast symmetry procedure with unilateral breast reconstruction using DIEP flaps. About 33 cases. Ann Chir Plast Esthet 2015; 60 (06) 472-477
- 9 Stevenson TR, Goldstein JA. TRAM flap breast reconstruction and contralateral reduction or mastopexy. Plast Reconstr Surg 1993; 92 (02) 228-233
- 10 Huang JJ, Wu CW, Leon Lam W, Lin CY, Nguyen DH, Cheng MH. Simultaneous contralateral breast reduction/mastopexy with unilateral breast reconstruction using free abdominal flaps. Ann Plast Surg 2011; 67 (04) 336-342
- 11 Inbal A, Gur E, Otremski E. et al. Simultaneous contralateral breast adjustment in unilateral deep inferior epigastric perforator breast reconstruction. J Reconstr Microsurg 2012; 28 (05) 285-292
- 12 Haykal S, Guay N. One hundred forty-one consecutive attempts at autologous tissue single-stage breast cancer reconstruction. Ann Plast Surg 2009; 63 (01) 21-27
- 13 Wade RG, Marongiu F, Sassoon EM, Haywood RM, Ali RS, Figus A. Contralateral breast symmetrisation in unilateral DIEP flap breast reconstruction. J Plast Reconstr Aesthet Surg 2016; 69 (10) 1363-1373
- 14 Fischer JP, Fox JP, Nelson JA, Kovach SJ, Serletti JM. A longitudinal assessment of outcomes and healthcare resource utilization after immediate breast reconstruction-comparing implant- and autologous-based breast reconstruction. Ann Surg 2015; 262 (04) 692-699
- 15 Fischer JP, Sieber B, Nelson JA. et al. Comprehensive outcome and cost analysis of free tissue transfer for breast reconstruction: an experience with 1303 flaps. Plast Reconstr Surg 2013; 131 (02) 195-203
- 16 Voss EA, Ma Q, Ryan PB. The impact of standardizing the definition of visits on the consistency of multi-database observational health research. BMC Med Res Methodol 2015; 15: 13
- 17 Veronesi U, Cascinelli N, Mariani L. et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 2002; 347 (16) 1227-1232
- 18 Fisher B, Redmond C, Poisson R. et al. Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med 1989; 320 (13) 822-828
- 19 Carbine NE, Lostumbo L, Wallace J, Ko H. Risk-reducing mastectomy for the prevention of primary breast cancer. Cochrane Database Syst Rev 2018; 4 (04) CD002748
- 20 Boughey JC, Attai DJ, Chen SL. et al. Contralateral prophylactic mastectomy (CPM) consensus statement from the American Society of Breast Surgeons: data on CPM outcomes and risks. Ann Surg Oncol 2016; 23 (10) 3100-3105
- 21 Panchal H, Matros E. Current trends in postmastectomy breast reconstruction. Plast Reconstr Surg 2017; 140 (5S): 7S-13S
- 22 Osman F, Saleh F, Jackson TD, Corrigan MA, Cil T. Increased postoperative complications in bilateral mastectomy patients compared to unilateral mastectomy: an analysis of the NSQIP database. Ann Surg Oncol 2013; 20 (10) 3212-3217
- 23 Chadab TM, Bernstein JL, Lifrieri A, Ascherman JA, Grant RT, Rohde CH. Is it worth the risk? contralateral prophylactic mastectomy with immediate bilateral breast reconstruction. Ann Plast Surg 2021; 87 (Suppl. 01) S2-S6
- 24 Miller ME, Czechura T, Martz B. et al. Operative risks associated with contralateral prophylactic mastectomy: a single institution experience. Ann Surg Oncol 2013; 20 (13) 4113-4120
- 25 Pinell-White XA, Kolegraff K, Carlson GW. Predictors of contralateral prophylactic mastectomy and the impact on breast reconstruction. Ann Plast Surg 2014; 72 (06) S153-S157
- 26 Momoh AO, Cohen WA, Kidwell KM. et al. Tradeoffs associated with contralateral prophylactic mastectomy in women choosing breast reconstruction: results of a prospective multicenter cohort. Ann Surg 2017; 266 (01) 158-164
- 27 Rosenberg SM, Tracy MS, Meyer ME. et al. Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey. Ann Intern Med 2013; 159 (06) 373-381
- 28 Silva AK, Lapin B, Yao KA, Song DH, Sisco M. The effect of contralateral prophylactic mastectomy on perioperative complications in women undergoing immediate breast reconstruction: a NSQIP analysis. Ann Surg Oncol 2015; 22 (11) 3474-3480
- 29 Alderman AK, Hawley ST, Waljee J, Mujahid M, Morrow M, Katz SJ. Understanding the impact of breast reconstruction on the surgical decision-making process for breast cancer. Cancer 2008; 112 (03) 489-494
- 30 King TA, Sakr R, Patil S. et al. Clinical management factors contribute to the decision for contralateral prophylactic mastectomy. J Clin Oncol 2011; 29 (16) 2158-2164
- 31 Albornoz CR, Matros E, Lee CN. et al. Bilateral mastectomy versus breast-conserving surgery for early-stage breast cancer: the role of breast reconstruction. Plast Reconstr Surg 2015; 135 (06) 1518-1526
- 32 Albornoz CR, Bach PB, Mehrara BJ. et al. A paradigm shift in U.S. breast reconstruction: increasing implant rates. Plast Reconstr Surg 2013; 131 (01) 15-23
- 33 Lippman ME, Wood WC. . In: Spear SL. ed. The Surgery of the Breast: Principles and Art. Philadelphia, PN: Lippincott-Raven; 2006. :Chapter 47: 658-659
- 34 Al-Ghazal SK, Sully L, Fallowfield L, Blamey RW. The psychological impact of immediate rather than delayed breast reconstruction. Eur J Surg Oncol 2000; 26 (01) 17-19
- 35 Elder EE, Brandberg Y, Björklund T. et al. Quality of life and patient satisfaction in breast cancer patients after immediate breast reconstruction: a prospective study. Breast 2005; 14 (03) 201-208
- 36 Heimes AS, Stewen K, Hasenburg A. Psychosocial aspects of immediate versus delayed breast reconstruction. Breast Care (Basel) 2017; 12 (06) 374-377
- 37 Salgarello M, Visconti G, Barone-Adesi L, Franceschini G, Masetti R. Contralateral breast symmetrisation in immediate prosthetic breast reconstruction after unilateral nipple-sparing mastectomy: the tailored reduction/augmentation mammaplasty. Arch Plast Surg 2015; 42 (03) 302-308
- 38 Bitoiu B, Grigor E, Hardy J, Zeitouni C, Arnaout A, Zhang J. Symmetric breast surgery: balancing procedures versus prophylactic mastectomy and immediate reconstruction. Plast Reconstr Surg 2024; 153 (04) 777-784
- 39 Rizki H, Nkonde C, Ching RC, Kumiponjera D, Malata CM. Plastic surgical management of the contralateral breast in post-mastectomy breast reconstruction. Int J Surg 2013; 11 (09) 767-772
- 40 Nelson JA, Voineskos SH, Qi J. et al. Elective revisions after breast reconstruction: results from the mastectomy reconstruction outcomes consortium. Plast Reconstr Surg 2019; 144 (06) 1280-1290
- 41 Eom JS, Kobayashi MR, Paydar K, Wirth GA, Evans GR. The number of operations required for completing breast reconstruction. Plast Reconstr Surg Glob Open 2014; 2 (10) e242
- 42 Chang EI, Selber JC, Chang EI. et al. Choosing the optimal timing for contralateral symmetry procedures after unilateral free flap breast reconstruction. Ann Plast Surg 2015; 74 (01) 12-16
- 43 Mirzabeigi MN, Smartt JM, Nelson JA, Fosnot J, Serletti JM, Wu LC. An assessment of the risks and benefits of immediate autologous breast reconstruction in patients undergoing postmastectomy radiation therapy. Ann Plast Surg 2013; 71 (02) 149-155
- 44 Chatterjee JS, Lee A, Anderson W. et al. Effect of postoperative radiotherapy on autologous deep inferior epigastric perforator flap volume after immediate breast reconstruction. Br J Surg 2009; 96 (10) 1135-1140
- 45 Kronowitz SJ, Hunt KK, Kuerer HM. et al. Delayed-immediate breast reconstruction. Plast Reconstr Surg 2004; 113 (06) 1617-1628
- 46 Chetta MD, Aliu O, Zhong L. et al. Reconstruction of the irradiated breast: a national claims-based assessment of postoperative morbidity. Plast Reconstr Surg 2017; 139 (04) 783-792
- 47 Rochlin DH, Matros E, Shamsunder MG, Rubenstein R, Nelson JA, Sheckter CC. Plastic surgery market share of breast reconstructive procedures: an analysis of two nationwide databases. J Surg Oncol 2023; 128 (07) 1064-1071