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DOI: 10.1055/a-1878-7795
Synthetic Strategies Towards the Meroterpenoids Cochlearols A and B from Ganoderma cochlear
This work was supported by the National Science Foundation (NSF CHE-1654223), the Alfred P. Sloan Foundation, the David and Lucile Packard Foundation, and the Camille and Henry Dreyfus Foundation (fellowships to C.S.S.).
Abstract
Since the first reports of their isolation, the meroterpenoids cochlearol A and B have attracted interest from the synthetic community for their unique structural features. This review describes the attempted and successful total syntheses of these natural products and provides a summary of the strategies developed in the years since their isolation.
1 Introduction
2 Overview of Cochlearol A Syntheses
3 Tong’s Approach Towards Cochlearol A
4 Liu and Qin’s Total Synthesis of (±)-Cochlearol A
5 Ishigami’s Formal Synthesis of (±)-Cochlearol A
6 Chandrasekhar’s Formal Synthesis of (±)-Cochlearol A
7 Sugita’s Synthesis of (±)-Cochlearol B
8 Schindler’s Synthesis of (+)-Cochlearol B
9 Conclusions
Publikationsverlauf
Eingereicht: 18. Mai 2022
Angenommen nach Revision: 20. Juni 2022
Accepted Manuscript online:
20. Juni 2022
Artikel online veröffentlicht:
09. März 2023
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