Synlett 2022; 33(10): 903-906
DOI: 10.1055/a-1741-8898
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Zwitterionic Metal Enolates or Equivalents: Generation and Capture

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Abstract

Functionalized ketones and their derivatives are important building blocks in organic synthesis and materials chemistry. The development of novel methods for the chemo-, regio-, diastereo-, stereo-, and enantioselective synthesis of functionalized ketones and their derivatives is a continuing endeavor of organic chemists. Here, we highlight a new approach recently initiated and developed by our group for the synthesis of (enantioenriched) ketones and related derivatives that is based on zwitterionic metal enolate chemistry.

1 Introduction

2 Annulations through Zwitterionic Palladium Enolate Chemistry for the Synthesis of Functionalized Cyclic Ketones

3 Nucleophilic Capture of Zwitterionic Metal (Palladium or Copper) Enolates or Their Equivalents

4 Conclusion



Publication History

Received: 01 January 2022

Accepted after revision: 16 January 2022

Accepted Manuscript online:
16 January 2022

Article published online:
08 February 2022

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