Synlett 2021; 32(13): 1303-1308
DOI: 10.1055/a-1344-5998
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Perspectives on Organoheteroatom and Organometallic Chemistry

Recent Progress in the Gold-Catalyzed Annulations of Ynamides with Isoxazole Derivatives via α-Imino Gold Carbenes

Long Li
a   Institute of New Materials & Industry Technology, College of Chemistry &Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. of China
,
Wen-Feng Luo
a   Institute of New Materials & Industry Technology, College of Chemistry &Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. of China
,
Long-Wu Ye
b   The Key Laboratory for Chemical Biology of Fujian Province & State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. of China
c   State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P. R. of China
› Author Affiliations

We are grateful for the financial support from the National Natural Science Foundation of China (21772161 and 21622204) and Wenzhou University.


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Abstract

During the past two decades, gold-catalyzed nitrene-transfer reactions via α-imino gold carbenes have received extensive attention, as this strategy provides rapid access to nitrogen-containing molecules with high efficiency. In this review, we focus on recent progress in gold-catalyzed formal annulations of ynamides with isoxazole derivatives as nitrene-transfer reagents via α-imino gold carbenes in atom-economic and rapid construction of N-heterocycles.



Publication History

Received: 13 November 2020

Accepted after revision: 02 January 2021

Accepted Manuscript online:
02 January 2021

Article published online:
05 February 2021

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