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Dtsch Med Wochenschr 2020; 145(23): 1673-1682
DOI: 10.1055/a-1114-3946
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Antibiotikatherapie im klinischen Alltag

Rational antimicrobial therapy – recommendations for common infections
Annette Hennigs
,
Johannes Jochum
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Infektionskrankheiten sind ein häufiger Grund für Arztkontakte im ambulanten Bereich und auch für Mortalität im Krankenhaus [1]. Dieser Beitrag erläutert die antibiotische Therapie von Infektionskrankheiten, die in der klinischen Praxis häufig vorkommen, und gibt praktische Handlungsempfehlungen. Infektionen, die komplexe und sehr unterschiedliche Behandlungsregime und interdisziplinäre Therapieentscheidungen benötigen, sind bewusst ausgenommen.

Abstract

Infectious diseases are a frequent reason for medical consultations both in the inpatient and outpatient setting. Inadequate management is associated with increased costs, morbidity and mortality. In times of rising antibiotic resistance rational therapy and antimicrobial stewardship are of utmost importance. While it is crucial to avoid excessively broad antimicrobial coverage and unnecessary therapies, serious conditions must be treated effectively. The article highlights common infections and gives recommendations for empiric and targeted antibiotic treatment. Discussed are pulmonary, abdominal, urinary tract, skin and soft tissue infections, as well as sepsis and staphylococcal bloodstream infections. The recommendations consider national and international guidelines, recent publications and current antimicrobial resistance in Germany.

Schlüsselwörter

Antibiotika - antibakterielle Therapie - Antibiotic Stewardship - Erwachsene

Key words

antibiotics - antibacterial agents - antimicrobial stewardship - adult


Publication History

Article published online:
17 November 2020

© 2020. Thieme. All rights reserved.

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