Abstract
Myositis is a rare and an extremely heterogeneous autoimmune disease, that causes
muscle weakness. Currently, “idiopathic inflammatory myopathies (IIM)“ is the preferred
umbrella-term used to describe the disease complexity within individuals. IIM include
dermatomyositis, polymyositis, inclusion body myositis, autoimmune necrotizing myopathy,
overlap myositis and antisynthetase syndrome. Research activity concerning myositis
was very intense over the past ten years and led to new diagnostic approach as well
as to novel therapeutic strategies. Correct classification is the key for successful
management. One single treatment regime for every possible organ involvement in all
different forms of IIM is still not existing.
Idiopathische inflammatorische Myopathien sind seltene heterogene Autoimmunerkrankungen,
die mit einer Muskelschwäche einhergehen. Kommen zur Muskelschwäche Haut- oder Allgemeinsymptome
wie Fatigue und Fieber hinzu oder andere Auffälligkeiten, sollten Behandelnde aufmerksam
werden. Dieser Beitrag stellt die wesentlichen Erkenntnisse zu Diagnose und Therapie
der Erkrankung mit ihren komplexen unterschiedlichen Unterformen vor.
Schlüsselwörter
Myositis - Dermatomyositis - Antisynthetase-Syndrom - idiopathische inflammatorische
Myopathien
Key words
myositis - dermatomyositis - antisynthetase syndrome - idiopathic inflammatory myopathies
