32. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber

Abdelbaky, HR

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Abdelraouf, HS

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Abramovic, K

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Adam, L

Natural course and prognostic factors in patients with cholestatic liver disease – experience from a single center study

Adjaye, J

Comparative induction of pluripotency in human umbilical vein endothelial cells and dermal fibroblasts and further differentiation into Hepatocytes

Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Ahmadian, MR

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Albrecht, U

Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Alexander, A

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Alhama, M

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Ali, ME

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Al-Kassou, B

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Allweiss, L

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Al Masaoudi, M

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Alt, Y

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Amin, E

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

Andersen, JB

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Andrié, R

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Annweiler, K

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Appenrodt, B

Die Bedeutung des renalen Resistance-Index für das Nierenversagen nach den neuen Kriterien bei Leberzirrhose

Arslanow, A

Two week protein-enriched low-calorie diet shows rapid improvement of fatty liver as assessed by controlled attenuation parameter

Asimakopoulou, A

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Augustin, H

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Aygul, S

Ammoniak induziert NADPH-Oxidase 4- vermittelt oxidativen Stress in kultivierten Rattenastrozyten

Baba, HA

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Baier, KM

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Balakrishnan, A

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

Bañares, R

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Bangen, JM

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice

Bantel, H

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

IFN-mediated cytokine induction is associated with sustained virological response in chronic HCV infection

Barbier, O

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Barikbin, R

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Barreiros, AP

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Bartels, M

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Bartenschlager, R

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression

The Hepatitis C Virus (HCV) results in an increased attraction of human neutrophils to its host cell by a basal and EGF-induced CXCR2 ligand expression

Bartneck, M

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Promotion of macrophage activation and inflammation in chronic liver disease by the histidine-rich glycoprotein

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Bartsch, D

CUX1 in liver cancer: experimental study in hypoxia model

Bauer, T

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Bechmann, LP

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Bechstein, WO

The value of intraoperative White-Test for biliary leakage following hepatic resection

Behnke, K

Role of new pathways in liver regeneration after acute and chronic liver damage

Beißbarth, T

Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model

Benito, Y

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Benten, D

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Benz, F

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Berg, T

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

The HLA-DPA1 rs3077 TT polymorphism is associated with spontaneous resolution of hepatitis B virus (HBV) infections in Caucasians

Bergen, M von

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Berger, C

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Berger, T

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Berkowski, C

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Bermejo, J

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Bernsmeier, A

Prevalence and Etiology of Elevated Aminotransferases in a Cohort of Patients referred to a German University Hospital

Berres, ML

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Berthold, C

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Bertoletti, A

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Beschorner, N

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Bettinger, D

Natural course and prognostic factors in patients with cholestatic liver disease – experience from a single center study

Beuke, K

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Bidmon, HJ

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Bierwolf, J

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Bilzer, M

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Bissinger, M

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Blümel, S

CUX1 in liver cancer: experimental study in hypoxia model

Boaru, SG

Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD

Bocuk, D

Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model

Bode, J

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Bode, JG

Identifikation neuer differenziell regulierter Mediatoren im Rahmen der Leberregeneration

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression

The Hepatitis C Virus (HCV) results in an increased attraction of human neutrophils to its host cell by a basal and EGF-induced CXCR2 ligand expression

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Boehm, S

The HLA-DPA1 rs3077 TT polymorphism is associated with spontaneous resolution of hepatitis B virus (HBV) infections in Caucasians

Boekschoten, MV

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Boesecke, C

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Boettler, T

Natural course and prognostic factors in patients with cholestatic liver disease – experience from a single center study

Characterization and functional modulation of HBV-specific CD4+ T cell responses

Bohle, RM

Severe drug-induced liver injury related to therapy with dimethyl fumarate

Böhm, S

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

Böhmer, F

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Bohner, A

Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen

Bonus, M

α5β1 Integrins are Receptors for Bile Acids with a (Nor-)Ursodeoxycholane Scaffold

Borkham-Kamphorst, E

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Bosserhoff, AK

Processing of MIA2 is important for its tumor suppressor function in hepatocellular carcinoma

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Böttler, T

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Bowe, A

Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11

Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr

Brach, J

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Brackertz, B

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Brandenburg, LO

FPR1 might play a relevant role in prevention of liver fibrosis

Breitkopf-Heinlein, K

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Bremer, B

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Bremer, CM

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Breuhahn, K

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Broering, R

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Broschewitz, J

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Brossart, P

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Brückner, S

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Brunner, SM

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Bruns, T

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Buchholz, F

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Büchter, M

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Buggisch, P

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Calvisi, DF

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Nuclear ErbB2 Expression of Hepatocytes in Alcoholic Steatohepatitis as Response to Cellular Stress Events

Camargo, R

Insulin-induced cytokine production as potential contributor to hepatic insulin resistance

Campos, G

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Identification of transcriptional regulatory networks in acute liver damage and regeneration

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Canbay, A

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Canbay, AE

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Canli, O

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Cantore, M

Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate

Carambia, A

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Castoldi, M

The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks

Differential modulation of vesicular and non-vesicular associated microRNAs isolated from sera of partially hepatectomized rats

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Castven, D

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Catalina, MV

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Cederbaum, AI

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Chalupsky, K

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Chamulitrat, W

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx

The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling

Deficiency of Group VIA phospholipase A2 Primes the Cytokine Releases by Kupffer cells and Lymphocytes

Chandhok, G

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Chang, J

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Chemnitz, J

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Chen, S

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Chen, X

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Chintalapati, C

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Christ, B

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Churin, Y

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Cigliano, A

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Coleman, CD

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Cornberg, M

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Cubero, FJ

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Curth, HM

Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11

Czauderna, C

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Dahmen, U

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Damm, G

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Dammermann, W

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Dandri, M

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Davis, RJ

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Dayoub, R

Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease

Antiapoptotic and antioxidative protein ALR in Cholestatic Liver Diseases – Do bile acids regulate ALR expression via Egr1?

de Bruin, A

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Dechêne, A

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Dediulia, T

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Deenen, R

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Deep Sharma, A

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

Deichsel, D

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

Dembek, C

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Demir, M

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Denzer, U

Fibrosis regression in autoimmune hepatitis

Deutschmann, K

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Dewidar, B

Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway

Dietel, C

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Dietz, J

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Di Fazio, P

CUX1 in liver cancer: experimental study in hypoxia model

Ding, J

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Ditze, M

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Dombrowski, F

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Nuclear ErbB2 Expression of Hepatocytes in Alcoholic Steatohepatitis as Response to Cellular Stress Events

Dominguez, MP

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Donner, M

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Dooley, S

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Dorbath, D

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Döring, P

Nuclear ErbB2 Expression of Hepatocytes in Alcoholic Steatohepatitis as Response to Cellular Stress Events

Dorn, C

Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression

Dreher, B

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Drescher, HK

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Dröge, C

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis

Dropmann, A

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Ebert, M

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Ehling, J

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Ehlken, H

Fibrosis regression in autoimmune hepatitis

Ehlting, C

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Ehrenmann, PS

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Elkady, MS

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Engel, B

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Engelmann, C

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Ensari, GK

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Ensenauer, R

Arginase 1 deficiency: long-term follow-up of the original patients

Ergen, C

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Evert, K

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Evert, M

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Falk, C

IFN-mediated cytokine induction is associated with sustained virological response in chronic HCV infection

Falk, CS

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Fech, V

Promotion of macrophage activation and inflammation in chronic liver disease by the histidine-rich glycoprotein

Feng, T

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Fettelschoss, A

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Feuer, R

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Fichtner-Feigl, S

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Fickert, P

Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr

Fimmers, R

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Finkelmeier, F

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Finnemann, C

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Fischer, HP

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Fischer, J

The HLA-DPA1 rs3077 TT polymorphism is associated with spontaneous resolution of hepatitis B virus (HBV) infections in Caucasians

Fischer, M

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Fischer, P

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Flecken, T

Characterization and functional modulation of HBV-specific CD4+ T cell responses

Fleet, JC

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Fokong, S

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Fölsch, UR

Prevalence and Etiology of Elevated Aminotransferases in a Cohort of Patients referred to a German University Hospital

Fox, IJ

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Franz, J

The value of intraoperative White-Test for biliary leakage following hepatic resection

Frau, M

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Freese, K

Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression

Friedrich, K

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Frieg, B

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Fülöp, A

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Fürst, G

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Gabor, I

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Gaestel, M

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Gaitantzi, H

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Galle, PR

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Gan-Schreier, H

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling

Gassler, N

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Gautheron, J

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Gebauer, S

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Gebhardt, R

Up and Down of Hedgehog Signaling leads to Down and Up of Steroidogenesis in the Liver

Konnex von Leber und Fettgewebe via Hedgehog Signalweg?

Gehrke, N

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Geier, A

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Geissler, EK

Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)

Gekle, M

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Gerken, G

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Gertzen, CGW

Binding Mode Prediction and Validation of Bile Acid and Neurosteroid Agonists of TGR5

Geyer, P

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Ghallab, A

Identification of transcriptional regulatory networks in acute liver damage and regeneration

Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy

Ghallab, AG

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Giebeler, A

FPR1 might play a relevant role in prevention of liver fibrosis

Giersch, K

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Gittel, C

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Glaser, F

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Glässner, A

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Glebe, D

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Godoy, P

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Identification of transcriptional regulatory networks in acute liver damage and regeneration

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Godoy, PG

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Goeppert, B

Association of immune cell infiltration and tumor suppression in hepatocellular carcinoma

Goeser, F

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Goeser, T

Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11

Gohlke, H

α5β1 Integrins are Receptors for Bile Acids with a (Nor-)Ursodeoxycholane Scaffold

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Binding Mode Prediction and Validation of Bile Acid and Neurosteroid Agonists of TGR5

Gomez-Quiroz, LE

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Görg, B

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen

Ammoniak induziert NADPH-Oxidase 4- vermittelt oxidativen Stress in kultivierten Rattenastrozyten

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Görtzen, J

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Gotthardt, D

Aggressive systemic mastocytosis of the liver with cholangitis

Gotthardt, DN

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Götz, E

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Götze, S

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Beyond fibrosis: stellate cells as liver stem cells

Epigenetic changes contribute to hepatic stellate cell activation

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Grabowski, J

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Graf, D

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Graffmann, N

Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

Grambihler, A

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Greinert, R

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Gress, T

CUX1 in liver cancer: experimental study in hypoxia model

Greten, FR

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Griesshammer, E

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Groos-Sahr, K

Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen

Gröpper, C

The Hepatitis C Virus (HCV) results in an increased attraction of human neutrophils to its host cell by a basal and EGF-induced CXCR2 ligand expression

Großmann, M

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Grotemeyer, K

Die Bedeutung des renalen Resistance-Index für das Nierenversagen nach den neuen Kriterien bei Leberzirrhose

Grundhoff, A

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Grüner, I

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Grünhage, F

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Grusdat, MD

The diverse functions of transcription factors in T cell immunity during LCMV infection

Guha, C

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Guldiken, N

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Günther, R

Prevalence and Etiology of Elevated Aminotransferases in a Cohort of Patients referred to a German University Hospital

Guthke, R

Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease

Haas, U

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Hall, RA

Multiple quantitative trait loci modeling (MQM) of hepatic fibrosis in a murine intercross

Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen

Hammad, S

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Hammel, A

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Hammer, S

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Hammerich, L

Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice

Hänze, J

CUX1 in liver cancer: experimental study in hypoxia model

Hao, F

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Hardtke, S

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Hardtke-Wolenski, M

The liver microcirculation might be important in promoting autoimmune hepatitis via maintaining an inflammatory cytokine milieu – A mathematical model study

Häring, MT

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Hartl, J

Fibrosis regression in autoimmune hepatitis

Hartmann, A

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Hartmann, D

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Hassan, R

Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy

Hatting, M

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Hauber, J

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Häussinger, D

Identifikation neuer differenziell regulierter Mediatoren im Rahmen der Leberregeneration

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

α5β1 Integrins are Receptors for Bile Acids with a (Nor-)Ursodeoxycholane Scaffold

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Arginase 1 deficiency: long-term follow-up of the original patients

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Differential modulation of vesicular and non-vesicular associated microRNAs isolated from sera of partially hepatectomized rats

Binding Mode Prediction and Validation of Bile Acid and Neurosteroid Agonists of TGR5

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis

Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen

Ammoniak induziert NADPH-Oxidase 4- vermittelt oxidativen Stress in kultivierten Rattenastrozyten

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Beyond fibrosis: stellate cells as liver stem cells

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression

Epigenetic changes contribute to hepatic stellate cell activation

The Hepatitis C Virus (HCV) results in an increased attraction of human neutrophils to its host cell by a basal and EGF-induced CXCR2 ligand expression

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection

Hay, DC

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Haybaeck, J

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Heemcke, J

Heterologous, costimulation-assisted vaccinations drive potent cellular immune responses to cancer

Heeren, J

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Heikenwälder, M

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Heilmann, S

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Heine, A

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Heinrich, S

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Hellerbrand, C

Processing of MIA2 is important for its tumor suppressor function in hepatocellular carcinoma

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression

Helmrich, NL

Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs

Hempel, M

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Hengstler, J

Identification of transcriptional regulatory networks in acute liver damage and regeneration

Hengstler, JG

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Henkel, C

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Henkel, J

Insulin-induced cytokine production as potential contributor to hepatic insulin resistance

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Herath, E

Die Bedeutung des renalen Resistance-Index für das Nierenversagen nach den neuen Kriterien bei Leberzirrhose

Herebian, D

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Herkel, J

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Hermanns, H

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Hermanns, HM

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Herr, M

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Herrmann, E

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Herweg, L

Die Bedeutung des renalen Resistance-Index für das Nierenversagen nach den neuen Kriterien bei Leberzirrhose

Herzer, K

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Heymann, F

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Hildt, E

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Hillebrandt, KH

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Hittatiya, K

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Hoevelmeyer, N

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Hoffmann, A

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Hoffmann, V

Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11

Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr

Hofmann, B

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Hofmann, E

CUX1 in liver cancer: experimental study in hypoxia model

Höhne, J

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Hollenbach, M

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Homey, B

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Homeyer, N

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Höner zu Siederdissen, C

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Hopf, C

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Hornung, M

Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)

Horst, A

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Horst, AK

Influence of the microbiome in regulating ConA-induced-liver injury

Hoss, M

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Hov, J

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Hu, W

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Huang, J

Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection

Huber, M

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Huber, S

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Hunka, L

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Hüppe, D

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Huynh, KC

Platelet integrin-dependent fibrillogenesis of fibronectin: Impact of shear stress

Shear-induced fibrillar-like supramolecule of plasma fibronectin: A new form of fibronectin with enhanced activity in platelet adhesion and aggregation

Ibrahim, S

Antiapoptotic and antioxidative protein ALR in Cholestatic Liver Diseases – Do bile acids regulate ALR expression via Egr1?

Ilkavets, I

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Indenbirken, D

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Inhoffen, J

Deficiency of Group VIA phospholipase A2 Primes the Cytokine Releases by Kupffer cells and Lymphocytes

Irmler, P

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Itzel, T

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Erhöhte Mortalität durch leberspezifische Koexpression der profibrogenetischen Faktoren PDGF-B und TGF-b

Jacobi, F

Characterization and functional modulation of HBV-specific CD4+ T cell responses

Jacobi, FJ

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Jäger, J

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Jahn, D

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

James, LP

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Jansen, C

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Jansen, J

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Jiao, L

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

Jochum, C

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

John, C

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Jöhrens, K

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Jouy, F

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Jüngst, C

The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Severe drug-induced liver injury related to therapy with dimethyl fumarate

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Kaczmarek, DJ

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Kah, J

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Kahraman, A

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Kaifie, A

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Kaiser, R

Inadequate vitamin D levels are not associated with dietary vitamin D intake in patients with chronic liver diseases but correlate with reduced light exposure as quantified by actigraphy

Kakoschky, B

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Kalinichenko, V

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Kalkhof, S

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Kanzler, S

Erhöhte Mortalität durch leberspezifische Koexpression der profibrogenetischen Faktoren PDGF-B und TGF-b

Karababa, A

Ammoniak induziert NADPH-Oxidase 4- vermittelt oxidativen Stress in kultivierten Rattenastrozyten

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Karimi, K

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Hepatocyte dependent induction of regulatory T-cell subsets

Karimova, M

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Karlsen, T

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Kaufmann, R

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Kawala, MA

Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Keitel, V

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

Determining the molecular consequences of clinically relevant glutamine synthetase mutations

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Binding Mode Prediction and Validation of Bile Acid and Neurosteroid Agonists of TGR5

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis

TGR5 knockout mice are highly susceptible to LCA induced liver damage

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Kesselring, R

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Kessler, SM

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Khawar, MB

Effect of paper industry leachate on various serological indices and serum proteins

Kiehntopf, M

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Kiemer, AK

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Kiessling, F

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Kiraithe, MM

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Kirchner, T

Aggressive systemic mastocytosis of the liver with cholangitis

Kirschner, J

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Kislat, A

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Klattig, J

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Klein, S

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Klindt, C

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Klinke, S

Aggressive systemic mastocytosis of the liver with cholangitis

Klinker, H

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Kluge, M

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Kluge, S

Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis

Kluwe, J

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Knaub, M

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Knodel, MM

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Knoefel, WT

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

Knolle, P

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Knop, V

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Kobazi Ensari, G

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Koch, A

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Koh, S

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Köhn-Gaone, J

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Köhrer, K

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Kokordelis, P

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

König, C

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

König, S

Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model

Koppe, C

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Köppel, A

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Kordes, C

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

Differential modulation of vesicular and non-vesicular associated microRNAs isolated from sera of partially hepatectomized rats

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Beyond fibrosis: stellate cells as liver stem cells

Epigenetic changes contribute to hepatic stellate cell activation

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Korf, HW

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Koschmieder, S

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Koukoulioti, E

The HLA-DPA1 rs3077 TT polymorphism is associated with spontaneous resolution of hepatitis B virus (HBV) infections in Caucasians

Kraft, ARM

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Krämer, B

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Krauel, A

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

Kraus, D

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Kraus, M

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Krause, P

Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model

Krawczyk, M

The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Krech, T

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Kreißl-Kemmer, S

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Krenkel, O

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Krieg, A

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

Kriegel, C

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Kristin, S

Regulation des Energiestoffwechsels in Hepatozyten durch Morphogene

Kronenberger, B

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Kroy, DC

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Kruk, B

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Krupp, M

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Kubitz, R

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Sequencing of ATP8B1, ABCB11 and ABCB4 revealed 135 genetic variants in 374 unrelated patients with suspected intrahepatic cholestasis

Kummer, U

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Kuna, M

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Kündig, T

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Küppers-Munther, B

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Kuscuoglu, D

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Kuttkat, N

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Lahiri, P

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Laleman, W

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Lambertz, J

Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD

Lammers, T

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Lammert, F

The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Die Bedeutung des renalen Resistance-Index für das Nierenversagen nach den neuen Kriterien bei Leberzirrhose

Severe drug-induced liver injury related to therapy with dimethyl fumarate

Two week protein-enriched low-calorie diet shows rapid improvement of fatty liver as assessed by controlled attenuation parameter

Multiple quantitative trait loci modeling (MQM) of hepatic fibrosis in a murine intercross

Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen

Six-month vitamin D replacement reduces hepatic steatosis in the absence of weight loss

Inadequate vitamin D levels are not associated with dietary vitamin D intake in patients with chronic liver diseases but correlate with reduced light exposure as quantified by actigraphy

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Lang, H

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

Lang, JK

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Lang, KS

Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection

Lang, PA

Role of new pathways in liver regeneration after acute and chronic liver damage

iRhom2 regulates specific activation and trafficking of TACE and enhances the survival of TNF α mediated septic shock after LPS treatment

The diverse functions of transcription factors in T cell immunity during LCMV infection

Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection

Lange, UG

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Langhans, B

Ascites total protein may be modulated by the use of diuretics

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Laschtowitz, A

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Lashin, AH

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Latte, G

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Lautem, A

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Leder, A

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Lee, JS

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Lee, S

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

Lee, SM

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Lefebvre, E

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Lehmann, J

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Leserer, S

Identification of transcriptional regulatory networks in acute liver damage and regeneration

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Lettmann, KA

The liver microcirculation might be important in promoting autoimmune hepatitis via maintaining an inflammatory cytokine milieu – A mathematical model study

Levada, K

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Leypoldt, L

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Li, L

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Li, Y

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway

Liebe, R

The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Liedtke, C

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Liepelt, A

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Linhart, M

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Linke, R

The value of intraoperative White-Test for biliary leakage following hepatic resection

Lippert, S

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Löhr, H

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Lohse, AW

Fibrosis regression in autoimmune hepatitis

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Luch, A

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Luedde, T

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Luft, S

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Lukowski, K

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Lüllmann-Rauch, R

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Lunemann, S

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Lüscher, B

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Lütgehetmann, M

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

Lüth, S

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Lütjohann, D

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Lutz, P

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Lutz, T

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Maass, T

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Erhöhte Mortalität durch leberspezifische Koexpression der profibrogenetischen Faktoren PDGF-B und TGF-b

Macias-Rodriguez, RU

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Madlen, MS

Regulation des Energiestoffwechsels in Hepatozyten durch Morphogene

Mahli, A

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Mais, C

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Major, RD

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Mak, TW

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Maney, SM

iRhom2 regulates specific activation and trafficking of TACE and enhances the survival of TNF α mediated septic shock after LPS treatment

Manka, P

Spleen and liver stiffness measurement using transient elastography correlates well with hypertensive upper gastrointestinal bleeding risk – an evaluation of 143 patients

Manns, MP

Heterologous, costimulation-assisted vaccinations drive potent cellular immune responses to cancer

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

IFN-mediated cytokine induction is associated with sustained virological response in chronic HCV infection

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Manowsky, J

Insulin-induced cytokine production as potential contributor to hepatic insulin resistance

Marchan, R

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Maria, G

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

Marinescu, AG

Prevalence and Etiology of Elevated Aminotransferases in a Cohort of Patients referred to a German University Hospital

Marquardt, J

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Marquardt, JU

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Matter, M

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Matz, P

Comparative induction of pluripotency in human umbilical vein endothelial cells and dermal fibroblasts and further differentiation into Hepatocytes

Matz-Soja, M

Up and Down of Hedgehog Signaling leads to Down and Up of Steroidogenesis in the Liver

Konnex von Leber und Fettgewebe via Hedgehog Signalweg?

Mauss, S

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Mayatepek, E

Arginase 1 deficiency: long-term follow-up of the original patients

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Maybüchen, L

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Mayer, PGK

Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate

McLauchlan, J

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Megges, M

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Meindl-Beinker, N

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Meiners, J

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Melter, M

Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease

Antiapoptotic and antioxidative protein ALR in Cholestatic Liver Diseases – Do bile acids regulate ALR expression via Egr1?

Mengel, E

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Merkel, M

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Mertens, M

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Metzger, G

CUX1 in liver cancer: experimental study in hypoxia model

Meurer, SK

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells

Meyer, C

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Michl, P

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Mielke, S

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Milkiewicz, P

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Mohs, A

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Moro, N

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Morsi, EA

Study of the relationship between explant histopathology and hepatocellular carcinoma post living donor liver transplantation

Morten, CH

Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr

Mossanen, JC

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Muller, M

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Müller, A

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Müller, J

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Müller, M

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Müller, S

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Müllhaupt, B

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Nägel, A

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Nahon, P

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

Nakhaei-Rad, S

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Nakhaeizadeh, H

The impact of the interaction between Embryonic stem cell-expressed Ras and Arginase-1 in hepatic stellate cells

Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells

Napierala, H

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Nattermann, J

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Naumann, U

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Neß, M

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells

Neumann, K

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Hepatocyte dependent induction of regulatory T-cell subsets

Neumann, U

FPR1 might play a relevant role in prevention of liver fibrosis

Neumann, UP

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Neumann-Haefelin, C

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Nevzorova, YA

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Nguyen, H

Shear-induced fibrillar-like supramolecule of plasma fibronectin: A new form of fibronectin with enhanced activity in platelet adhesion and aggregation

Nguyen, HTT

Platelet integrin-dependent fibrillogenesis of fibronectin: Impact of shear stress

Shear-related fibrillogenesis of fibronectin

Nguyen-Tat, M

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Nick, E

Inadequate vitamin D levels are not associated with dietary vitamin D intake in patients with chronic liver diseases but correlate with reduced light exposure as quantified by actigraphy

Nickenig, G

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Niemietz, C

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Nierhoff, D

Different mouse models of oval cell induction can lead to reactivation of the oncofetal marker Neighbor of Punc E 11

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr

Nischalke, HD

Ascites total protein may be modulated by the use of diuretics

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Nuraldeen, R

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

Nussler, A

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Oenarto, J

Ammoniak induzierte miRNA Expressionsänderungen in kultivierten Rattenastrozyten

Oreffo, R

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Ostroumov, D

Heterologous, costimulation-assisted vaccinations drive potent cellular immune responses to cancer

Ott, M

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

Otto, G

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Paluschinski, M

The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks

Pankow, F

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Papapostoli, I

Six-month vitamin D replacement reduces hepatic steatosis in the absence of weight loss

Pascale, RM

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Passmann, S

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Pathil, A

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling

Pathil-Warth, A

Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx

Patsenker, E

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Paul, A

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Peiffer, KH

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Peiseler, M

Fibrosis regression in autoimmune hepatitis

Peng, J

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Perner, D

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Petersen, J

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Pfaff, M

Hepatocyte dependent induction of regulatory T-cell subsets

Philipp, L

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Pietsch, UC

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Piiper, A

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Pilo, GM

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Nuclear ErbB2 Expression of Hepatocytes in Alcoholic Steatohepatitis as Response to Cellular Stress Events

Pinna, F

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Plat, J

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Pleli, T

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Ploeger, C

Association of immune cell infiltration and tumor suppression in hepatocellular carcinoma

Pohl, S

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Pohlmann, AP

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Polgar, Z

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Pollok, JM

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Pratschke, J

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Preis, R

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Preisinger, C

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Protzer, U

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Proudfoot, A

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Puerto, M

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Püngel, T

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Püschel, GP

Insulin-induced cytokine production as potential contributor to hepatic insulin resistance

Development of a new modified western diet to induce NASH with obesity and insulin resistance in mice

Pütter, L

Identification of transcriptional regulatory networks in acute liver damage and regeneration

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Quagliata, L

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Ramadori, P

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Raschzok, N

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Rashidi-Alavijeh, J

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Raszeja-Wyszomirska, J

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Rattay, S

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Rau, M

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Rauber, C

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Rausch, M

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Real, CI

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Rebholz, C

Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen

Rehders, A

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Reich, M

Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors

TGR5 knockout mice are highly susceptible to LCA induced liver damage

Reichert, M

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Reichert, MC

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Reif, R

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy

Reisinger, F

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Reißing, J

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Reiter, S

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Rennert, C

Up and Down of Hedgehog Signaling leads to Down and Up of Steroidogenesis in the Liver

Konnex von Leber und Fettgewebe via Hedgehog Signalweg?

Reuken, PA

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Reul, WH

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Reutzel-Selke, A

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Rey, J

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Rey, JW

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Ribback, S

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice

Riedel, A

Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)

Rincón, D

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Ring, S

Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

Rinker, F

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Ripoll, C

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Rizzo, LY

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Rochlitz, K

Identification of transcriptional regulatory networks in acute liver damage and regeneration

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage

Rockstroh, JK

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Roderburg, C

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Roderfeld, M

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Rodriguez, LZ

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Roeb, E

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Roessler, S

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Association of immune cell infiltration and tumor suppression in hepatocellular carcinoma

Rolf, G

Regulation des Energiestoffwechsels in Hepatozyten durch Morphogene

Rose-John, S

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Roy, S

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Roy-Chowdhury, J

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Roy-Chowdhury, N

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Rubner, C

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Rufat, P

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

Ruiz-Margain, A

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Rümmele, P

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Rupp, C

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Aggressive systemic mastocytosis of the liver with cholangitis

Rupp, M

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Russo, C

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Saftig, P

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Sahin, H

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Sahle, S

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Salcedo, M

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Sallmon, H

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Santosa, D

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Sanwald, J

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Sarrazin, C

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Sastre Turrión, B

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Sauer, IM

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Sauer, P

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Sauer, V

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Saugspier, M

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

Sawitza, I

Differential modulation of vesicular and non-vesicular associated microRNAs isolated from sera of partially hepatectomized rats

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Beyond fibrosis: stellate cells as liver stem cells

Sawodny, O

Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis

Schäfer, C

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Scharbatke, EC

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Scharf, RE

Platelet integrin-dependent fibrillogenesis of fibronectin: Impact of shear stress

Shear-related fibrillogenesis of fibronectin

Shear-induced fibrillar-like supramolecule of plasma fibronectin: A new form of fibronectin with enhanced activity in platelet adhesion and aggregation

Schattenberg, J

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Schattenberg, JM

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Scherbaum, N

Comparative analysis of CD1 d-restricted natural killer T cells in people who inject drugs with chronic or spontaneously resolved hepatitis C

Schierwagen, R

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Schildberg, F

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Schiller, B

Influence of the microbiome in regulating ConA-induced-liver injury

Schirdewahn, T

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Schirmacher, P

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Aggressive systemic mastocytosis of the liver with cholangitis

Association of immune cell infiltration and tumor suppression in hepatocellular carcinoma

A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment

Schlaak, JF

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Schlaphoff, V

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Schlitt, HJ

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)

Schlune, A

Arginase 1 deficiency: long-term follow-up of the original patients

Schmidt, HHJ

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Schmidt, L

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Schmidt, M

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Schmidt-Arras, D

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Schmidt-Heck, W

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Identification of transcriptional regulatory networks in acute liver damage and regeneration

Schmithals, C

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Schmitt, J

Vitamin D Receptor Modulates Intestinal Lipid Metabolism, Adipose Tissue Inflammation and Hepatic Steatosis in Diet-induced Obese Mice

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Schneider, F

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Schnitzbauer, AA

The value of intraoperative White-Test for biliary leakage following hepatic resection

Schott, T

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Schramm, C

Fibrosis regression in autoimmune hepatitis

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Redundant tolerance mechanisms prevent autoimmune liver inflammation in mice

Schreier, B

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Schubert, S

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Schulte am Esch, J

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Schulze-Osthoff, K

IFN-mediated cytokine induction is associated with sustained virological response in chronic HCV infection

Schulze zur Wiesch, J

CRISPR/Cas9 “double”-nickase mediated inactivation of hepatitis B virus replication

Schumacher, EC

Epigenetic changes contribute to hepatic stellate cell activation

Schupp, AK

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Schwarze-Zander, C

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Schwinge, D

A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury

Sebode, M

Fibrosis regression in autoimmune hepatitis

Seddek, A

Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy

Sedlacek, R

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Seehofer, D

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Seitz, HK

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Seiz, PL

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Sekyere, SO

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Senff, T

Comparative analysis of CD1 d-restricted natural killer T cells in people who inject drugs with chronic or spontaneously resolved hepatitis C

Shafigullina, A

Ammoniak hemmt die LPS-induzierte Mikrogliaaktivierung und Transkription pro-inflammatorischer Zytokine in Astrozyten/Mikroglia Kokulturen

Sheikh, N

Effect of paper industry leachate on various serological indices and serum proteins

Shen, Z

Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway

Siefert, J

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Singer, S

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Sini, M

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Sivanathan, V

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Solanki, M

Processing of MIA2 is important for its tumor suppressor function in hepatocellular carcinoma

Sollinger, D

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Sommer, L

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Sommerfeld, A

α5β1 Integrins are Receptors for Bile Acids with a (Nor-)Ursodeoxycholane Scaffold

Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate

Sonntag, R

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Sotlar, K

Aggressive systemic mastocytosis of the liver with cholangitis

Spengler, U

Ascites total protein may be modulated by the use of diuretics

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Spitzhorn, LS

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Spitzley, S

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression

Spomer, L

Binding Mode Prediction and Validation of Bile Acid and Neurosteroid Agonists of TGR5

The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)

Sprinzl, M

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Sprinzl, MF

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Staffer, S

Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx

Stallmach, A

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Steffen, BT

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Steffens, H

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Stella, J

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Stengel, SH

Comparative analysis of inflammatory biomarkers in spontaneous bacterial peritonitis and acute-on-chronic liver failure

Stickel, F

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Stindt, J

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Stindt, S

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression

Stoeber, R

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Stokes, CS

Two week protein-enriched low-calorie diet shows rapid improvement of fatty liver as assessed by controlled attenuation parameter

Six-month vitamin D replacement reduces hepatic steatosis in the absence of weight loss

Inadequate vitamin D levels are not associated with dietary vitamin D intake in patients with chronic liver diseases but correlate with reduced light exposure as quantified by actigraphy

Stoldt, V

Shear-induced fibrillar-like supramolecule of plasma fibronectin: A new form of fibronectin with enhanced activity in platelet adhesion and aggregation

Stoldt, VR

Platelet integrin-dependent fibrillogenesis of fibronectin: Impact of shear stress

Shear-related fibrillogenesis of fibronectin

Strand, S

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Strassburg, C

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Strassburg, CP

Ascites total protein may be modulated by the use of diuretics

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Straub, BK

Aggressive systemic mastocytosis of the liver with cholangitis

Streetz, KL

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Stremmel, W

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx

The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling

Deficiency of Group VIA phospholipase A2 Primes the Cytokine Releases by Kupffer cells and Lymphocytes

Strnad, P

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Strücker, B

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Su, J

The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling

Suneetha, PV

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Susser, S

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Sutton, A

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

Tacke, F

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Promotion of macrophage activation and inflammation in chronic liver disease by the histidine-rich glycoprotein

Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Tal, A

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Talab, AA

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Tang, P

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

Tar, K

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Targett-Adams, P

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Tautenhahn, HM

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Tchaikovskaya, T

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Teuber, G

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Teufel, A

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Tumor infiltrating B cells producing antitumor active immunoglobulins in resected hepatocellular carcinoma prolong patient survival

Erhöhte Mortalität durch leberspezifische Koexpression der profibrogenetischen Faktoren PDGF-B und TGF-b

Teutsch, M

Two week protein-enriched low-calorie diet shows rapid improvement of fatty liver as assessed by controlled attenuation parameter

Thasler, WE

Autophagy impairment and ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

A steatotic environment promotes the progression of hepatocellular carcinoma via direct and indirect mechanisms

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression

Thimme, R

The breadth of CD8+ T cell responses in chronic and resolved HBV infection

Natural course and prognostic factors in patients with cholestatic liver disease – experience from a single center study

Characterization and functional modulation of HBV-specific CD4+ T cell responses

Thomas, B

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Thomas, M

Identifikation neuer differenziell regulierter Mediatoren im Rahmen der Leberregeneration

Regulation des Energiestoffwechsels in Hepatozyten durch Morphogene

Thonig, A

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Thöns, C

Comparative analysis of CD1 d-restricted natural killer T cells in people who inject drugs with chronic or spontaneously resolved hepatitis C

Thorgeirsson, SS

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Analysis of transcriptomic changes during cold ischaemia in time-zero biopsies of liver allografts

Tiegs, G

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Hepatocyte dependent induction of regulatory T-cell subsets

Influence of the microbiome in regulating ConA-induced-liver injury

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Tihaa, L

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Tiller, T

Characterization of recombinant human monoclonal antibodies against the Bile Salt Export Pump

Timm, J

Comparative analysis of CD1 d-restricted natural killer T cells in people who inject drugs with chronic or spontaneously resolved hepatitis C

Tirnitz-Parker, JEE

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Tony, HP

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Topp, SA

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Trautwein, C

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

In alcoholic cirrhosis, low serum hepcidin levels associate with poor long-term survival and higher occurrence of hepatocellular carcinoma

The platelet-derived chemokine CXCL4 exerts protective role in non-alcoholic steatohepatitis (NASH) in vivo

Accumulation of hepatitis B surface antigen promotes the development of alpha-1 antitrypsin mutation-related liver disease

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert die Infiltration pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der akuten Leberschädigung

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Promotion of macrophage activation and inflammation in chronic liver disease by the histidine-rich glycoprotein

Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice

Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung

Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Trebicka, J

Heart rate variability and heart rate turbulence correlated with the complications and the progress of cirrhosis and might predict the outcome of cirrhotic patients

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Trojan, J

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Trottier, J

Delayed intrahepatic cholestasis induced by anabolic steroids in a patient with haploinsufficiency of the pregnane X receptor (PXR/NR1I2)

Tsay, HC

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

Tschuschner, A

Tauroursodeoxycholsäure aktiviert das Ubiquitin-Proteasom System in Hepatitis B transgenen Zellen

Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs

Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten

Tuma-Kellner, S

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

Deficiency of Group VIA phospholipase A2 Primes the Cytokine Releases by Kupffer cells and Lymphocytes

Uder, C

Stammzelltherapie bei ausgedehnter Leberresektion im Schwein

Ulrich, F

The value of intraoperative White-Test for biliary leakage following hepatic resection

Uschner, FE

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Utpatel, K

Different oncogenic potential in the mouse liver of mutant forms of the p110alpha catalytic subunit of phosphoinositide-3-kinase (PIK3CA)

Early ultrastructural hepatocellular alterations after hydrodynamic tail vein injection

Vaillant, A

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

van Bömmel, F

The distribution of surface antigen (HBsAg) components can distinguish between inactive carriers and active forms of Hepatitis B virus (HBV) infections

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Quantification of serum HBV RNA allows differentiation of disease stages of hepatitis B virus (HBV) infections

The HLA-DPA1 rs3077 TT polymorphism is associated with spontaneous resolution of hepatitis B virus (HBV) infections in Caucasians

Van de Leur, E

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Vella, G

Hsp72 overexpression protects from drug-induced- and lipotoxic liver injury

Venna, V

Fibrosis regression in autoimmune hepatitis

Verheugd, P

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Vermehren, A

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Vermehren, J

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Vlaic, S

Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease

Voetlause, R

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Vogel, A

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Volz, T

Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice

Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice

vom Dahl, S

Arginase 1 deficiency: long-term follow-up of the original patients

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Vonnahme, M

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Vossbeck, J

Prevalence of the sphingolipid storage diseases M. Gaucher and M. Niemann-Pick type B: results in a nation-wide screening project in 224 patients

Vucur, M

Die Kinase RIPK1 vermittelt eine neue molekulare Interaktion zwischen Entzündung und Zelltod in der Hepatokarzinogenese und Cholestase

Waidmann, O

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Waisman, A

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Waldburger, N

Aggressive systemic mastocytosis of the liver with cholangitis

Association of immune cell infiltration and tumor suppression in hepatocellular carcinoma

Walle, H

Two week protein-enriched low-calorie diet shows rapid improvement of fatty liver as assessed by controlled attenuation parameter

Walter, S

Deficiency of the oncostatin M receptor affects the pathogenesis of non-alcoholic fatty liver disease in a context dependent manner

Walther, T

Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis

Wammers, M

Bile acid-modulated transcript-expression in human macrophages validated by transcriptome analysis

Wan, F

LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells

Wan, S

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Wandrer, F

IFN-mediated cytokine induction is associated with sustained virological response in chronic HCV infection

Wang, JM

FPR1 might play a relevant role in prevention of liver fibrosis

Wang, X

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Wannhoff, A

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx

Warzecha, KT

Microbubbles as used for contrast-enhanced ultrasound affect the migration of human primary leukocytes

Weber, B

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Weber, MM

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

Weber, SN

Die lithogene Variante D19 H im Cholsterintransporter Abcg8 führt zu verminderter Phospholipidsekretion in Mäusen

Wedemeyer, H

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Induction of innate and adaptive immune responses after stopping NA therapy in HBeAg negative chronic hepatitis B

Wege, H

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Wegscheid, C

A pro-inflammatory role of type 2 innate lymphoid cells in murine immune-mediated hepatitis

Influence of the microbiome in regulating ConA-induced-liver injury

Wehmeyer, M

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Wei, W

Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation

Weigert, A

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Weiler, S

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Weiler-Normann, C

Fibrosis regression in autoimmune hepatitis

Weinmann, A

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Weiskirchen, R

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

Weiss, J

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Weiss, KH

Improved survival in patients with primary sclerosing cholangitis and normalization of serum cholestasis markers after biliary dilatation therapy

Weiss, T

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Hepatic gene expression profile characterizes high levels of liver regeneration related genes in nonalcoholic fatty liver disease

Antiapoptotic and antioxidative protein ALR in Cholestatic Liver Diseases – Do bile acids regulate ALR expression via Egr1?

Weißbrich, B

Hepatitis B Reaktivierung unter Chemotherapie und Immunsuppression – eine monozentrische Studie an 4868 Patienten

Wells, RG

Differential activation of RhoA and c-SRC in experimental and human fibrosis

Welzel, T

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Weng, H

Wisp1 as an early stage marker of human hepatocellular carcinoma (HCC)?

Weng, HL

Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway

Werner, JM

Innate Immune Cell Activation in a Human in-vitro Model of Nonalcoholic Steatohepatitis (NASH)

Werner, M

Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells

Poly I:C-stimulated human non-parenchymal liver cells are potent suppressors of hepatitis C virus replication

Werner, T

Sicherheit und Effektivität eines getunnelten Verweilkatheters zur Aszitesdrainage bei Patienten mit Leberzirrhose und therapierefraktärem Aszites mit Kontraindikationen zur TIPS-Anlage

Wetzel, S

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Wewering, F

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Widera, A

Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

Identification of transcriptional regulatory networks in acute liver damage and regeneration

Widera, AB

WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)

Wieczorek, K

Aggressive systemic mastocytosis of the liver with cholangitis

Willuweit, K

Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis

Winkler, S

Identifizierung angiogener Faktoren nach Applikation von Hep3B mit mesenchymalen Stammzellen in der immundefizienten Maus

Wirth, T

Heterologous, costimulation-assisted vaccinations drive potent cellular immune responses to cancer

Wissenbach, DKWK

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Wissniowski, T

CUX1 in liver cancer: experimental study in hypoxia model

Witthöft, T

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Wittum, G

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

Wöhler, C

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

Wohlfahrt, J

Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model

Wöhner, B

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis

Wolf, A

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Wolf, D

γ-GT is associated with splanchnic thrombotic events, CRP predicts survival in patients with myeloproliferative neoplasms

Wolf, S

Identifikation neuer differenziell regulierter Mediatoren im Rahmen der Leberregeneration

Wolf, T

Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1

Wolff, A

Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model

Wolter, F

HIV Mono-Infektion ist mit gestörter Anti-HCV-Aktivität von NK-Zellen assoziiert

Assoziation des IL28B Polymorphismus mit dem Ausmaß der Monozyten-induzierten NK Zell-Aktivierung bei der Hepatitis C

Charakterisierung des NK-Zellpools bei HIV/HCV-koinfizierten Patienten

Wörns, M

Ginkgo biloba differentially affects untransformed and malignant cells in the liver

Induction of stemness features and activation of prognostically adverse genomic alterations in hepatocellular carcinoma by field cancerization

Wörns, MA

Hepatic B cell leukemia-3 attenuates chemically-induced hepatocarcinogenesis in mice

Die Therapie mit Terlipressin und Humanalbumin ist auch bei Patienten mit hepatorenalem Syndrom Typ 2 effektiv

Wranke, A

IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Wruck, W

Comparative induction of pluripotency in human umbilical vein endothelial cells and dermal fibroblasts and further differentiation into Hepatocytes

Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model

Xu, HC

Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection

Yotti, R

Real Time Pressure Volume Loops in Cirrhosis: Characterization of Systolic and Diastolic Function and Validation of Doppler Indices with the Gold Standard

Youssef, SA

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Yuan, Q

MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis

Zacarias-Föhrding, L

Salvage in situ liver transection (ISLT) for patients with unresectable liver tumors and insufficient volume increase of the future liver remnant after portal vein embolization

Zanger, UM

Identifikation neuer differenziell regulierter Mediatoren im Rahmen der Leberregeneration

Zehnter, E

Pre-existing co-morbidities and co-medications of patients undergoing treatment of chronic HCV G1 infection in German real-life

Efficacy and safety of Boceprevir triple therapy in previously treated patients with HCV Genotype 1 (G1) infection in German real-life

Boceprevir triple therapy of chronic HCV genotype 1 (G1) infection in previously untreated patients: Efficacy, predictability of virologic response and safety in German real-life

Treatment of chronic HCV Genotype 1 infection with Boceprevir in German real-life:The impact of SVR on initially elevated and initially normal serum alanine aminotransferase (ALT) and gamma-glutamyl transpeptidase (GGT) levels

Zellmer, S

A human hepatic in vitro co-culture system for the analysis of DILI related signaling

Zenouzi, R

Fibrosis regression in autoimmune hepatitis

Zeuzem, S

High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis

Genotypen-spezifische Prävalenz und Bedeutung natürlich vorkommender Precore-, Basal Core Promotor- und preS-Mutationen in einer großen europäischen Studienkohorte bei chronisch mit dem Hepatitis B Virus infizierten Patienten

Untersuchung des Langzeitverlaufs von Patienten mit einer niedrig-replikativen chronischen Hepatitis B-Infektion, die keine antivirale Therapie erhalten: 2 Jahres-Daten einer deutschen prospektiven Studie (ALBATROS Studie)

Selective targeting of tumor-associated macrophages in hepatocellular carcinoma

Zhang, W

Urine cell-derived hepatocyte-like cells as potential therapeutic cell transplants for different liver diseases

Zhao, G

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung

Zibert, A

Hepatocyte-like cell platforms for in vitro evaluation of antisense drugs in familial amyloidosis using stem cell technology

Zimmer, S

Simvastatin senkt die hepatische Inflammation und Fibrose in Apolipoprotein E Knock-out Mäusen nach sieben Wochen Western Diät

Zimmer, V

The power of NGS: Results from a dedicated sequencing panel of 24 genes in 40 patients with cholestatic liver disease

Procholestatic gene variants and mutations in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

FUT2 variant might modulate the course in secondary sclerosing cholangitis in critically ill patients (SC-CIP)

Zimmermann, A

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

Diminished Antiviral Cytokine Response in Bile Duct Ligated Mice

Zimmermann, HW

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

miR-1224 is upregulated in hepatic ischemia-reperfusion injury and induces cell death via Sp1 inhibition

Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Zimmermann, T

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

HCV-specific immune responses under direct-acting antiviral therapy of chronic HCV infection

Ziol, M

Keratin 23 represents a novel liver injury marker reflecting the severity of ductular reaction

Zipprich, A

Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis

Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks

Zobeley, C

Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation

Zoubek, ME

Verlust von Caspase 8 in Leberparenchymzellen schützt vor Obstruktiver Cholestase

Kombinierte Aktivitäten von JNK1 und JNK2 in Hepatozyten schützen vor Toxin-induzierten Leberschädigung