Synthesis 2008(11): 1685-1687  
DOI: 10.1055/s-2008-1067029
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Molybdenum(VI) Dichloride Dioxide Catalyzed Synthesis of β-Keto Esters by C-H Insertion of Ethyl Diazoacetate into Aldehydes

Kandasamy Jeyakumar, Dillip Kumar Chand*
Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India
Fax: +91(44)22574202; e-Mail: dillip@iitm.ac.in;
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Publikationsverlauf

Received 21 February 2008
Publikationsdatum:
16. April 2008 (online)

Abstract

Synthesis of β-keto esters by condensing various aldehydes with ethyl diazoacetate is achieved by using molybdenum(VI) dichloride dioxide. Aromatic, aliphatic, and heterocyclic aldehydes are successfully condensed with ethyl diazoacetate to obtain corresponding β-keto esters in high yields at room temperature.