Synthesis 2008(7): 1078-1084  
DOI: 10.1055/s-2008-1032125
© Georg Thieme Verlag Stuttgart · New York

Reaction of Huisgen Zwitterion with Diaryl Ketones Leading to the Facile Synthesis of Mono- and Bis(alkoxycarbonyl)hydrazones

Vijay Nair*, Smitha C. Mathew, Akkattu T. Biju, Eringathodi Suresh
Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (Formerly Regional Research Laboratory), CSIR, Trivandrum 695 019, India
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Further Information

Publication History

Received 16 August 2007
Publication Date:
06 March 2008 (eFirst)


The Huisgen zwitterion, generated from triphenylphosphine and dialkyl azodicarboxylates, afforded upon reaction with diaryl ketones both mono- and bis(alkoxycarbonyl)hydrazones, depending on the reaction conditions.