Synthesis 2008(7): 1078-1084  
DOI: 10.1055/s-2008-1032125
PAPER
© Georg Thieme Verlag Stuttgart · New York

Reaction of Huisgen Zwitterion with Diaryl Ketones Leading to the Facile Synthesis of Mono- and Bis(alkoxycarbonyl)hydrazones

Vijay Nair*, Smitha C. Mathew, Akkattu T. Biju, Eringathodi Suresh
Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (Formerly Regional Research Laboratory), CSIR, Trivandrum 695 019, India
Fax: +91(471)2491712; e-Mail: vijaynair_2001@yahoo.com;
Further Information

Publication History

Received 16 August 2007
Publication Date:
06 March 2008 (online)

Abstract

The Huisgen zwitterion, generated from triphenylphosphine and dialkyl azodicarboxylates, afforded upon reaction with diaryl ketones both mono- and bis(alkoxycarbonyl)hydrazones, depending on the reaction conditions.

    References

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9

The crystal structure data of compound 5b have been deposited at the Cambridge Crystallographic Data Centre and allocated the reference no. CCDC 650903.

10

The crystal structure data of compound 6d have been deposited at the Cambridge Crystallographic Data Centre and allocated the reference no. CCDC 650904.