Neue Therapieansätze bei Malaria: molekulare Aspekte der Erythrozyteninvasion

Schlüsselwörter

Malaria - Plasmodium spp. - Prophylaxe - intrazellulärer Parasitismus - Zellinvasion

Key words

Malaria - Plasmodium spp. - prophylaxis - intracellular parasitism - cell invasion

Literatur

• 1 Cowman A F, Crabb B S. Invasion of red blood cells by malaria parasites. Review.  Cell. 2006;  124 755-66
• 2 Gardner M J, Hall N, Fung E . et al . Genome sequence of the malaria parasite plasmodium falciparum.  Nature. 2002;  416 498-511
• 3 Good M F. Vaccine-induced immunity to malaria parasites and the need for novel strategies. Review.  Trends Parasitol. 2005;  21 29-34
• 4 Kouyaté B, Sie A, Ye M, De Allegri M, Müller O. The Great Failure of Malaria Control in Africa: A District Perspective from Burkina Faso.  PLoS Med. 2007;  4 e127

• 5 Kwiatkowski D P. How malaria has affected the human genome an what human genetics can teach us about malaria.  Am J Hum Genet. 2005;  77 171-192
• 6 O’Donnell R A, Hackett F, Howell S A, Treeck M, Struck N, Krnajski Z, Withers-Martinez C, Gilberger T W, Blackman M J. Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.  J Cell Biol. 2006;  174 1023-33
• 7 Snow R W, Guerra C A, Noor A M, Myint H Y, Hay S I. The global distribution of clinical episodes of Plasmodium falciparum malaria.  Nature. 2005;  434 214-7
• 8 Sturm A, Amino R, van de Sand C, Regen T, Retzlaff S, Rennenberg A, Krueger A, Pollok J M, Menard R, Heussler V T. Manipulation of host hepatocytes by the malaria parasite for delivery into liver sinusoids.  Science. 2006;  313 1287-90