Synfacts 2007(12): 1267-1267  
DOI: 10.1055/s-2007-991355
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

An Anion-Sensing Capsule

Contributor(s): Timothy M. Swager, Gaku Fukuhara
C. Olivier, Z. Grote, E. Solari, R. Scopelliti, K. Severin*
École Polytechnique Fédérale de Lausanne, Switzerland
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Publikationsverlauf

Publikationsdatum:
22. November 2007 (online)

Significance

The authors were able to synthesize macrocyclic host 3, which binds phosphate and acetate in aqueous solution at neutral pH. Five equivalents of LiOH were added to a solution of [(η6-benzene)RuCl2]2 as Ru complex 1 and bis(dihydroxypyridine) as ligand 2 in D2O to afford the water-soluble capsule 3 with a yield of >90%, as evidenced from in situ NMR spectroscopy.