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Synthesis 2007(24): 3858-3862  
DOI: 10.1055/s-2007-990890
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Pyrazole, Isoxazole, and Aminopyrimidine Ring-Fused Benzothiocycloheptane-Derived Oxazolidinones and Their Corresponding Sulfone Derivatives

Vladimir Khlebnikova, Samarendra N. Maiti*a, J. V. N. Vara Prasadb, Frederick E. Boyerb, Mike Stier b
a Naeja Pharmaceutical Inc., #2 4290-91A Street, Edmonton, AB, T6E 5V2, Canada
Fax: +1(780)4610196; e-Mail: smaiti@naeja.com;
b Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA
Further Information

Publication History

Received 1 June 2007
Publication Date:
15 November 2007 (online)

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Abstract

The synthesis of a series of pyrazole, isoxazole, and aminopyrimidine ring-fused benzothiocycloheptane-derived oxazolidinones and their corresponding sulfone derivatives is described.

Key words

antibiotics - heterocycles - fused-ring systems - oxazolidinones - bezothiocycloheptanone

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