Neue bildgebende Verfahren zur Diagnostik mukosaler Neoplasien

Zusammenfassung

Die makroskopische Beurteilung der Schleimhautoberfläche und die Kenntnis der Klassifikation von intestinalen Frühkarzinomen sollten zum Repertoire des endoskopierenden Arztes gehören. Durch Neuerungen in der Endoskopietechnik wird eine bessere Eingrenzung und Beurteilung pathologischer Schleimhautareale möglich, der diagnostische Gewinn in der Detektion durch Techniken wie NBI sollte jedoch nicht überschätzt werden. Verfahren wie Endozytoskopie oder Konfokale Lasermikroskopie werden in Studien evaluiert und haben durchaus das Potenzial in Zukunft möglicherweise eine Differenzierung von pathologischen Schleimhautarealen zu ermöglichen. Es ist jedoch bisher nicht möglich, dadurch die histologische Beurteilung durch den Pathologen zu ersetzen.

Abstract

The macroscopic aspect and the classification of intestinal early neoplasia should be part of every endoscopist knowledge. Modern endoscopic techniques like narrow band imaging (NBI) allow a better differentiation of pathological areas but diagnostic gain for the detection of intestinal neoplasia should not be overestimated. Endocytoscopy or confocal lasermicroscopy are evaluated in clinical studies. In the future they may have the potential to allow differentiation of pathological mucosal areas. The histological workup by a pathologist can not be replaced.

Schlüsselwörter

Frühkarzinome - Narrow-Band-Imaging - neue diagnostische Techniken

Key words

early neoplasia - narrow band imaging - new diagnostic techniques

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1 Erstautor: Prof. Dr. Helmut Messmann