Subscribe to RSS
DOI: 10.1055/s-2007-984946
© Georg Thieme Verlag KG Stuttgart · New York
Lunge und Autoimmunerkrankungen - Klinik und Diagnostik
Lung and autoimmune disease - clinic and diagnostic approachPublication History
                     eingereicht: 10.5.2007
                     
                     akzeptiert: 11.7.2007
                     
Publication Date:
20 July 2007 (online)

Zusammenfassung
Die Lunge ist bei vielen Autoimmunerkrankungen betroffen. Der vorliegende Übersichtsartikel stellt die pulmonalen Manifestationsformen der Vaskulitiden, rheumatischer Erkrankungen und Kollagenosen dar. Das klinische Bild und das diagnostische Vorgehen werden beschrieben.
Summary
Pulmonary involvement is commonly seen in autoimmune disease. In this review the clinical presentation of pulmonary involvement in vasculitis, rheumatoid arthritis and connective tissue disease is presented. Clinical symptoms and diagnostic approach will be discussed.
Schlüsselwörter
Alveolitis - Diffuse alveoläre Hämorrhagie - Fibrose - Kollagenose - Pulmonale Hypertonie - Vaskulitis
Key words
alveolitis - connective tissue disease - diffuse alveolar haemorrhage - fibrosis - pulmonary hypertension - vasculitis
Literatur
- 1 
            Cheema G S, Quismorio F P. 
            Interstitial lung disease in systemic lupus erythematodes. 
            Curr Opin Pulm Med. 
            2000; 
            6 
            424-429 
            
            Reference Ris Wihthout Link
- 2 
            Cordier J F, Valeyre D, Guillevin L. et al .
            Pulmonary WegenerŽs granulomatosis: a clinical and imaging study of 77 cases. 
            Chest. 
            1990; 
            97 
            906-912 
            
            Reference Ris Wihthout Link
- 3 
            El Maqhraoui A, Chaouir S, Abid A. et al .
            Lung findings on thoracic high-resolution computed tomography in patients with ankylosing
            spondylitis. Correlations with disease duration, clinical findings and pulmonary function
            testing. 
            Clin Rheumatol. 
            2004; 
            23 
            123-128 
            
            Reference Ris Wihthout Link
- 4 
            Fagan K A, Badesch D B. 
            Pulmonary hypertension associated with connective tissue disease. 
            Prog Cardiovasc Dis. 
            2002; 
            45 
            225-234 
            
            Reference Ris Wihthout Link
- 5 
            Frank S I, Weg J G, Harkleroas L E, Fitch R F. 
            Pulmonary dysfunction in rheumatoid arthritis. 
            Chest. 
            1973; 
            63 
            27-34 
            
            Reference Ris Wihthout Link
- 6 
            Guillevin L, Durand-Gasselin R, Cevallos M. et al .
            Microscopi polyangiits. Clinical and laboratory findings in eighty-five patients. 
            Arthritis Rheum. 
            1999; 
            42 
            421-430 
            
            Reference Ris Wihthout Link
- 7 
            Gross W L, Schmitt W H, Csernok E. 
            ANCA and associated diseases. Immunodiagnostic and pathogenetic aspects. 
            Clin Exp Immunol. 
            1992; 
            91 
            1-2 
            
            Reference Ris Wihthout Link
- 8 
            Hill C L, Zhang Y, Sigurgeirsson B. et al .
            Frequency of specific cancer types in dermatomyositis and polymyositis: a population-based
            study. 
            Lancet. 
            2001; 
            357 
            96-100 
            
            Reference Ris Wihthout Link
- 9 
            Hoffmann G S, Kerr G S, Leavitt R Y. et al .
            Wegener granulomatosis: an analysis of 158 patients. 
            Ann Intern Med. 
            1992; 
            116 
            488-498 
            
            Reference Ris Wihthout Link
- 10 
            Jayne D R, Gaskin C, Pusey C D. et al .
            ANCA and predicting relapse in systemic vasculitis. 
            Q J Med. 
            1995; 
            88 
            127-133 
            
            Reference Ris Wihthout Link
- 11 
            Manganelli P, Fietta P, Carotti M. et al .
            Respiratory system involvement in systemic vasculitides. 
            Clin Exp Rheumatol. 
            2006; 
            24 
            S48-59 
            
            Reference Ris Wihthout Link
- 12 
            Lee D M, Schur P H. 
            Clinical utility of the anti-CCP assay in patients with rheumatic diseases. 
            Ann Rheum Dis. 
            2003; 
            62 
            870-874 
            
            Reference Ris Wihthout Link
- 13 
            Parambil J G, Myers J L, Lindell R M, Matteson E L. et al .
            Interstitial lung disease in primary Sjögren syndrome. 
            Chest. 
            2006; 
            130 
            1439-1495 
            
            Reference Ris Wihthout Link
- 14 
            Prakash U B. 
            Respiratory complications in mixed connective tissue disease. 
            Clin Chest Med. 
            1998; 
            19 
            733-746 
            
            Reference Ris Wihthout Link
- 15 
            Reuter M, Schnabel A, Wesner F. et al .
            Pulmonary Wegener’s granulomatosis: correlation between high-resolution CT findings
            and clinical scoring of disease activity. 
            Chest. 
            1998; 
            114 
            500-506 
            
            Reference Ris Wihthout Link
Prof. Dr. med. Peter Zabel
         Medizinische Klinik, Forschungszentrum Borstel
         
         Parkallee 35
         
         23845 Borstel
         
         Phone: 04537/188301
         
         Fax: 04537/188313
         
         Email: pzabel@fz-borstel.de
         
         
 
     
      
    