Synthesis 2008(1): 155-160  
DOI: 10.1055/s-2007-983895
PSP
© Georg Thieme Verlag Stuttgart · New York

One-Pot Synthesis of Dihydroimidazo- and Imidazophenanthridinium Salts

Alexis D. C. Parenty*, Leroy Cronin*WestCHEM, University of Glasgow, Chemistry Department, Glasgow, G12 8QQ, UK
Fax: +44(141)3304888; e-Mail: alexisp@chem.gla.ac.uk; e-Mail: l.cronin@chem.gla.ac.uk;
Further Information

Publication History

Received 15 February 2007
Publication Date:
11 September 2007 (eFirst)

Abstract

Two highly efficient and general one-pot annulation reactions are described for the synthesis of dihydroimidazo- and imidazophenanthridinium salts (DIPs + and IPs +). These two methodologies exploit the difference in reactivity between primary amino-based or ammonia nucleophiles and the dielectrophilic starting material, 2-bromoethylphenanthridinium bromide.