Synthesis 2007(8): 1197-1203  
DOI: 10.1055/s-2007-965977
PAPER
© Georg Thieme Verlag Stuttgart · New York

A One-Pot, Stereoselective Synthesis of 1,3- and 1,4-Dienyl Sulfones by Hydrostannylation-Stille Tandem Reaction of Tributyltin Hydride with Acetylenic Sulfones and Alkenyl or Allylic Halides

Mingzhong Cai*, Guiqin Chen, Wenyan Hao
School of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P. R. of China
Fax: +86(791)8120388; e-Mail: caimzhong@163.com;
Further Information

Publication History

Received 9 January 2007
Publication Date:
23 March 2007 (online)

Abstract

1,3-Dienyl and 1,4-dienyl sulfones can be stereoselectively synthesized in one pot under mild conditions, in good yields, by the palladium-catalyzed hydrostannylation of acetylenic sulfones, followed by Stille coupling with alkenyl or allylic halides, respectively.