Eur J Pediatr Surg 2007; 17(6): 428-430
DOI: 10.1055/s-2007-965810
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

Penile Malignant Peripheral Nerve Sheath Tumour (Schwannoma) in a Three-Year-Old Child without Evidence of Neurofibromatosis

A. Mortell1 , B. Amjad2 , F. Breatnach1 , D. Devaney2 , P. Puri1
  • 1Our Lady's Children's Hospital, Dublin, Ireland
  • 2The Children's University Hospital, Dublin, Irland
Further Information

Publication History

received May 14, 2007

accepted May 23, 2007

Publication Date:
11 December 2007 (online)

Abstract

Malignant schwannoma (malignant peripheral nerve sheath tumour, MPNST) is a rare high-grade tumour arising from peripheral nerves. We report the case of a 3-year-old male who presented with a non-tender lesion on the dorsum of his penis. The lesion was excised and a formal circumcision performed. Histology of the lesion revealed a spindle cell tumour. Immunohistochemistry showed the tumour cells to be strongly positive for S100 and Vimentin. A diagnosis of intermediate grade malignant peripheral nerve sheath tumour was made. Malignant schwannoma is rare in children and is previously unreported in the penis in the paediatric age group without evidence of neurofibromatosis.

References

Professor Prem Puri

Director of Research
Children's Research Centre
Our Lady's Children's Hospital

Crumlin

Dublin 12

Ireland

Email: [email protected]