Malignant schwannoma (malignant peripheral nerve sheath tumour, MPNST) is a rare high-grade
tumour arising from peripheral nerves. We report the case of a 3-year-old male who
presented with a non-tender lesion on the dorsum of his penis. The lesion was excised
and a formal circumcision performed. Histology of the lesion revealed a spindle cell
tumour. Immunohistochemistry showed the tumour cells to be strongly positive for S100
and Vimentin. A diagnosis of intermediate grade malignant peripheral nerve sheath
tumour was made. Malignant schwannoma is rare in children and is previously unreported
in the penis in the paediatric age group without evidence of neurofibromatosis.
penile - schwannoma - neurofibromatosis
