Synlett 2006(13): 2154-2155  
DOI: 10.1055/s-2006-948178
SPOTLIGHT
© Georg Thieme Verlag Stuttgart · New York

Triazolinediones (TADs)

Gholamabbas Chehardoli*
College of Chemistry, Bu-Ali Sina University, Hamadan 6517838683, Iran
e-Mail: cheh1002@gmail.com;
Further Information

Publication History

Publication Date:
09 August 2006 (online)

Introduction

4-Substituted-1,2,4-triazoline-3,5-diones (TADs, 2) were first synthesized by Thiele in 1894. [1] These compounds were prepared via oxidation of urazoles (1, Scheme 1). [2] Urazoles and their oxidation products (TADs) are commercially available. [3] Recently, several heterogeneous systems have been reported for the oxidation of urazoles to their corresponding triazolinediones. [4] Triazolinediones are red or pink crystalline solids which are very reactive and able to participate in a wide range of reactions such as [2+2] and [4+2] cycloadditions, ene reactions, and electrophilic aromatic substitutions, etc. [5-7]

Scheme 1

    References

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