Synlett 2006(11): 1753-1755  
DOI: 10.1055/s-2006-944205
LETTER
© Georg Thieme Verlag Stuttgart · New York

Electrochemical Cyclization of Dimethyl Aminomalonates

Mitsuhiro Okimoto*, Takashi Yoshida, Masayuki Hoshi, Kazuyuki Hattori, Masashi Komata, Kaori Numata, Kenta Tomozawa
Department of Applied and Environmental Chemistry, Kitami Institute of Technology, Koen-cho 165, Kitami, Hokkaido 090-8507, Japan
Fax: +81(0157)247719; e-Mail: oki@chem.kitami-it.ac.jp;
Further Information

Publication History

Received 28 March 2006
Publication Date:
04 July 2006 (online)

Abstract

Dimethyl aminomalonates were electrochemically oxidized in methanol to afford the corresponding cyclization products through the formation of carbon-carbon bonds. Optimum yields were obtained when NaCN was utilized as the supporting electrolyte at room temperature. Presumably, the electrooxidation involves a two-electron oxidation process.