DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2006; 131(19): 1091-1099DOI: 10.1055/s-2006-941727 CME-Beitrag | Review articleOnkologie/Gynäkologie© Georg Thieme Verlag KG Stuttgart · New YorkMammakarzinomBreast cancerB. Ataseven1 , W. Eiermann1 1Frauenklinik vom Roten Kreuz, München Recommend Article Abstract Buy Article Schlüsselwörter Mammakarzinom - Screening/Prävention, Therapie, Nachsorge Key words Breast cancer - Screening/prevention, therapy, aftercare Full Text References Literatur 1 Ries L. et al. National Cancer Institute .SEER cancer statistics review 1975 - 2001. URL http://seer.cancer.gov/csr/1975_2001/2004 2 Blanks R G, Moss S M, McGahan C E, Quinn M J, Babb P J. Effect of NHS breast screening programme on mortality from breast cancer in England and Wales, 1990 - 8: comparison of observed with predicted mortality. BMJ. 2000; 321 665-669 3 Verhoog L C, Brekelmans C TM, Seynaeve C. et al . Survival in hereditary breast cancer associated with germline mutations of BRCA 2. JCO. 1999; 17 3396-3402 4 Cuzick J, Forbes J, Edwards R. et al . First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial. Lancet. 2002; 360 817-824 5 Fisher B, Costantino J P, Wickerham D L. et al . Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst. 1998; 90 1371-88 6 Cauley J A, Norton L, Lippman M E. et al . Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat. 2001; 65 125-134 7 Eiermann W, Paepke S, Appfelstaedt J. et al . Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicenter study. Ann Oncol. 2001; 12 1527-532 8 Jonat W, Gnant M, Boccardo F, Kaufmann M, Rubagotti A, Jakesz R. Switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-responsive early breast cancer: a meta-analysis of th ARNO 95 Trial, ABCSG Trial 8, and the ITA Trial. Breast cancer Res Treat. 2005; 94 (suppl 1) , abstr 18 9 Coombes R C, Hall E, Gibson L J. et al . A Randomized Trial of Exemestane after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer. N Engl J Med. 2004; 350 1081-1092 10 Goss P E, Ingle J N, Martino S. et al . A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer. N Engl J Med. 2003; 349 1793-1802 11 Vicini F A, Horwitz E M, Lacerna M D. et al . The role of regional nodal irradiation in the management of patients with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 1997; 39 1069-1076 12 Gadd M, Harris J, Taghian A. et al . Prospective Study of axillary radiation without axillary dissection for breast cancer patients with a positive sentinel node. Breast cancer Res Treat. 2005; 94 (suppl 1) , abstr 22 13 Martin M, Pienkowski T, Mackey J. et al . Adjuvant docetaxel for node-positive breast cancer. Engl J Med. 2005; 352 2302-2313 14 Roche H, Fumoleau P, Spielmann M. et al . Five years analysis of the PACS 01 trial: 6 cycles of FEC100 vs 3 cycles of FEC 100 followed by 3 cycles of docetaxel (D) for the adjuvant treatment of node positive breast cancer. Breast cancer Res Treat. 2004; 88 (suppl 1) , abstr 27 15 Henderson I C, Berry D A, Demetri G D. et al . Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol. 2003; 21 976-983 Dr. med. Beyhan Ataseven Frauenklinik vom Roten Kreuz Taxisstraße 3 80637 München Phone: 089/15706620 Fax: 089/15706623 Email: beyhan.ataseven@swmbrk.de