Synthesis 2006(2): 221-223  
DOI: 10.1055/s-2005-918511
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

A New Regioselective Bromination of Activated Aromatic Rings

Leonardo S. de Almeida, Pierre M. Esteves*, Marcio C. S. de Mattos*
Instituto de Química, Departamento de Química Orgânica, Universidade Federal do Rio de Janeiro, Cx. Postal 68545, 21945-970 Rio de Janeiro, Brazil
Fax: +55(21)25627133; e-Mail: mmattos@iq.ufrj.br; e-Mail: pesteves@iq.ufrj.br;
Further Information

Publication History

Received 27 June 2005
Publication Date:
21 December 2005 (online)

Abstract

An efficient and highly regioselective bromination of activated aromatic rings promoted by tribromoisocyanuric acid by in situ generation of Br+ has been developed. A range of aromatic compounds were reacted with tribromoisocyanuric acid and trichloroisocyanuric acid and sodium bromide.