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Synthesis 2005(19): 3319-3326  
DOI: 10.1055/s-2005-918463
PAPER
© Georg Thieme Verlag Stuttgart · New York

The Synthesis of 1,2,3-Triazoles from Nitroalkenes - Revisited

Béatrice Quiclet-Sire*, Samir Z. Zard*
Laboratoire de Synthèse Organique associé au CNRS Ecole Polytechnique, 91128 Palaiseau, France
Fax: +33(1)69333851; e-Mail: zard@poly.polytechnique.fr;
Further Information

Publication History

Received 27 September 2005
Publication Date:
14 November 2005 (online)

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Abstract

Nitroalkenes or vicinal acetoxy nitro derivatives undergo a clean reaction with sodium azide in hot dimethyl sulfoxide to give the corresponding 1,2,3-triazoles in good yield.

Key words

azides - cyclisations - heterocycles - nitroalkenes - 1,2,3-triazoles

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