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Synthesis 2005(19): 3297-3300  
DOI: 10.1055/s-2005-918461
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Photoswitchable Hemithioindigo-Based ω-Amino Acids and Application in Boc-Based Peptide Assembly

Stephan Herre, Wencke Steinle, Karola Rück-Braun*
Institut für Chemie, Technische Universität Berlin, Str. d. 17. Juni 135, Sekr. C3, 10623 Berlin, Germany
Fax: +49(30)31479651; e-Mail: krueck@chem.tu-berlin.de;
Further Information

Publication History

Received 16 September 2005
Publication Date:
14 November 2005 (online)

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Abstract

Efficient procedures for the preparation of the N-Boc-protected aldehydes 5a and 5b are described which are valuable precursors for the synthesis of hemithioindigo-based ω-amino acids and peptides.

Key words

hemithioindigos - amino acids - peptides - photoswitches

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