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Synthesis 2005(20): 3502-3504
DOI: 10.1055/s-2005-918418
DOI: 10.1055/s-2005-918418
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York
The First Synthesis of a Diynone from Echinacea pallida
Further Information
Received
9 April 2005
Publication Date:
12 October 2005 (online)
Publication History
Publication Date:
12 October 2005 (online)
Abstract
In order to provide an authentic standard and to generate pure material for biological testing, an efficient synthetic route to 1 was developed. This represents the first total synthesis of a major bioactive diynone from E. pallida.
Key words
diynones - selective alkyne reduction - coupling reaction - selective desilylation
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