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Synfacts 2005(1): 0104-0104  
DOI: 10.1055/s-2005-872159
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Total Synthesis of Cryptophycin 3

Contributor(s): Philip Kocienski, Thomas Snaddon
P. Danner, M. Bauer, P. Phukan, M. E. Maier*
Universität Tübingen, Germany
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Publikationsdatum:
21. September 2005 (online)

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Significance

The cryptophycins are cyclodepsipeptides isolated from blue-green algae. They display a plethora of biological activity, which include antifungal and antitumor properties, the latter a consequence of the disruption of microtubule assembly.