Synthesis 2005(17): 2989-2993  
DOI: 10.1055/s-2005-872145
PSP
© Georg Thieme Verlag Stuttgart · New York

Nickel-in-Charcoal (Ni/C): An Efficient Heterogeneous Catalyst for the Construction of C-C, C-N, and C-H Bonds

Bryan A. Frieman, Benjamin R. Taft, Ching-Tien Lee, Tom Butler, Bruce H. Lipshutz*
Department of Chemistry, University of California, Santa Barbara, CA 93106, USA
Fax: +1(805)8938265; e-Mail: [email protected];
Further Information

Publication History

Received 24 June 2005
Publication Date:
04 August 2005 (online)

Abstract

The preparation and use of nickel-in-charcoal as an environmentally benign and inexpensive alternative to solution-based palladium­-catalyzed cross-couplings are described.

    References

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20

Microwave-accelerated heterogeneous cross-couplings based on Ni/C catalysis have been successfully used in Negishi, Suzuki, and amination reactions: Lipshutz, B. H.; Frieman, B. A.; Lee, C-T.; Nihan, D.; Taft B. R., manuscript in preparation.