A Novel Cleavage for Polystyrene-Supported Selenium Resins: An Efficient Route to 3,5-Disubstituted Isoxazolines and Their Derivatives

Wei-Ming Xu; Yu-Guang Wang; Mao-Zhong Miao; Xian Huang

doi:10.1055/s-2005-869971

PAPER

A Novel Cleavage for Polystyrene-Supported Selenium Resins: An Efficient Route to 3,5-Disubstituted Isoxazolines and Their Derivatives

Wei-Ming Xu^a,b, Yu-Guang Wang^a, Mao-Zhong Miao^a, Xian Huang*^a
^a Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou, 310028, P. R. China
Fax: +86(571)88807077; e-Mail: huangx@mail.hz.zj.cn;
^b Center of Analysis and Measurement, Zhejiang University, Hangzhou, 310028, P. R. China

Abstract

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Abstract

We report here a novel cleavage method for polystyrene-supported selenium resin using CH₃I-NaI under mild conditions to prepare 3,5-disubstituted isoxazolines. The polymer selenium resins can be reused without further transformation.

Keywords

heterocycles - selenium - cycloadditions - isoxazolines - solid-phase synthesis

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References

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