Synlett 2005(5): 0872-0874  
DOI: 10.1055/s-2005-864797
LETTER
© Georg Thieme Verlag Stuttgart · New York

A Versatile Method for the Hydrogen Peroxide Oxidation of Alcohols Using PTC Condition in tert-Butanol

Bhupender S. Chhikara, Ramesh Chandra, Vibha Tandon*
Medicinal Chemistry Research Laboratory, Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi-110007, India
Fax: +91(11)27666248; e-Mail: vibhadelhi@hotmail.com;
Further Information

Publication History

Received 17 August 2004
Publication Date:
09 March 2005 (online)

Abstract

An efficient protocol for the oxidation of secondary and primary alcohols to the corresponding ketones and aldehydes and/or carboxylic acids using hydrogen peroxide as oxidant is ­described. A quasi-homogenous reaction system was obtained by t-butanol as solvent to achieve high yield of the product in short time.