Synlett 2004(12): 2245-2246  
DOI: 10.1055/s-2004-832833
SPOTLIGHT
© Georg Thieme Verlag Stuttgart · New York

Phosphorus Pentasulfide (P4S10)

Vivek Polshettiwar*
Process Technology Development Division, Defence R & D ­Establishment, Jhansi Road, Gwalior, 474002 (MP) India.
e-Mail: vivekpol2002@rediffmail.com;
Further Information

Publication History

Publication Date:
21 September 2004 (online)

Introduction

Organosulfur compounds are valued not only for their rich and varied chemistry, but also for many important ­biological properties. Phosphorous pentasulfide (P4S10) is very useful and versatile reagent for the synthesis of ­various ­organosulfur compounds. P4S10 is widely available as a light yellow crystalline solid. It is highly flammable and decomposes in the presence of moisture.

P4S10 has been extensively used as a thionating agent for the conversion of carbonyls into thiocarbonyls in the preparation of organosulfur compounds. It also activates the free hydroxyl group of an acid or an alcohol to create a good leaving group. It can also be used as a deoxygenating and dehydrating agent.

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