Synlett 2004(13): 2445-2446  
DOI: 10.1055/s-2004-832831
SPOTLIGHT
© Georg Thieme Verlag Stuttgart · New York

Hydrazine Hydrate (NH2NH2·H2O)

Asheesh Kumar Jain*
Synthetic Chemistry Division, Defence Research and Development Estabishment, Gwalior (M.P.), 474002, India
e-Mail: jainashu29@rediffmail.com;
Further Information

Publication History

Publication Date:
24 September 2004 (online)

Introduction

The synthetic utilities of hydrazine hydrate have been extensively investigated in organic chemistry. Among reducing agents, hydrazine hydrate stands out for its application to a broad variety of reductive transformations. It is easy to use and reduces many functional groups, such as carbonyl compounds, alkenes, alkynes and nitro groups under mild reaction conditions. Hydrazine hydrate is commercially available. It is a liquid (mp -52 °C, bp 120-121 °C, d = 1.027 g/mL), and is ­soluble in water, ethanol, methanol, propanol and iso­butanol.

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