Copper-Mediated Simple and Efficient Synthesis of Tribenzohexadehydro[12]annulene and Its Derivatives

Abstract

A simple and efficient synthesis of tribenzohexadehydro[12]annulene and its derivatives was carried out using coupling reaction of acetylenes with iodoarenes in the presence of catalytic amounts of CuI and PPh₃, together with three equivalents of K₂CO₃ in DMF. This synthetic procedure was applied to the synthesis of a large annulenoannulene derivative.

annulenes - cross-coupling - cyclizations - macrocycles - oligomerization

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