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Dtsch Med Wochenschr 2004; 129(7): 321-326
DOI: 10.1055/s-2004-818629
Übersichten
Kardiologie
© Georg Thieme Verlag Stuttgart · New York

Sind Antioxidantien zur Behandlung der Atherosklerose sinnvoll?

Is the supplementation with antioxidants effective in the treatment of atherosclerosis?St Schröder1
  • 1Medizinische Klinik, Abteilung für Kardiologie (Direktor: Prof. Dr. L. Seipel), Eberhard-Karls-Universität Tübingen
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Publikationsverlauf

eingereicht: 9.7.2003

akzeptiert: 23.9.2003

Publikationsdatum:
05. Februar 2004 (online)

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Zusammenfassung

Die Ergebnisse experimenteller und epidemiologischer Studien legen nahe, dass dem oxidativen Stress in der Entstehung und Progression der Atherosklerose im Menschen eine wichtige Bedeutung zukommt. Diese konnte in prospektiven Endpunktstudien bislang nicht nachgewiesen werden. In der vorliegenden Übersicht wird der aktuelle Stand der Literatur zusammenfasst.

Summary

Results from experimental and epidemiologic studies suggest an influence of oxidative stress on development and progression of atherosclerosis in man. Prospective endpoint studies failed to support this hypothesis. The current literature is summarized in this review.

Literatur

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Priv.-Doz. Dr. Stephen Schröder

Medizinische Klinik Tübingen, Abteilung für Kardiologie

Otfried-Müller-Straße 10

72076 Tübingen

Telefon: 07071/2982711

Fax: 07121/478962

eMail: Stephen.Schroeder@med.uni-tuebingen.de