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Synthesis 2004(8): 1303-1305  
DOI: 10.1055/s-2004-815965
PSP
© Georg Thieme Verlag Stuttgart · New York

Reliable Protocol for the Large Scale Synthesis of Diphenylphosphoryl Azide (DPPA)

Oliver Wolff, Siegfried R. Waldvogel*
Westfälische Wilhelms-Universität Münster, Org.-Chem. Institut, Corrensstr. 40, 48149 Münster, Germany
Fax: +49(251)8339772; e-Mail: [email protected];
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Publication History

Received 29 December 2003
Publication Date:
10 February 2004 (online)

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Abstract

The preparation of analytically pure diphenylphosphoryl azide (DPPA) in 100 g scale is described in detail resulting in a very reliable protocol starting with the corresponding phosphoryl chloride.

Key words

azides - phosphorus - rearrangement - transfer reagent - synthesis

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