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Synthesis 2004(1): 106-110
DOI: 10.1055/s-2003-44364
DOI: 10.1055/s-2003-44364
PAPER
© Georg Thieme Verlag Stuttgart · New YorkInBr3-Catalyzed Conjugate Addition of Indoles to p-Quinones: An Efficient Synthesis of 3-Indolylquinones
Further Information
Received
31 July 2003
Publication Date:
09 December 2003 (online)
Publication History
Publication Date:
09 December 2003 (online)
Abstract
Indium(III) bromide catalyzes efficiently the conjugate addition of indoles to p-benzoquinones under mild conditions to afford the corresponding 3-indolylquinones in high yields with high selectivity. 1,4-Naphthoquinones also underwent Michael addition with indoles under similar conditions to give 3-indolylnaphthoquinones.
Key words
p-quinones - indoles - indium compounds - indol-3-ylbenzoquinones
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