Synlett 2003(15): 2395-2397  
DOI: 10.1055/s-2003-42097
LETTER
© Georg Thieme Verlag Stuttgart · New York

An Alternative Total Synthesis of (-)-Heliannuol E [1]

Tomoyo Kamei, Mitsuru Shindo, Kozo Shishido*
Institute for Medicinal Resources, University of Tokushima, 1-78 Sho-machi, Tokushima 770-8505, Japan
Fax: +81(88)6339575; e-Mail: shishido@ph2.tokushima-u.ac.jp;
Further Information

Publication History

Received 16 September 2003
Publication Date:
15 October 2003 (online)

Abstract

An efficient, enantiocontrolled total synthesis of (-)-heliannuol E has been accomplished using a palladium-catalyzed cyclization of the six-membered oxygen containing heterocycle as the key reaction step.

1

This work was presented at the 6th International Symposium on Biocatalysis and biotransformations, Olomouc, June 2003 (Abstract paper: P156).

1

This work was presented at the 6th International Symposium on Biocatalysis and biotransformations, Olomouc, June 2003 (Abstract paper: P156).