The Preparation of Vinylhydrazinedicarboxylates from Ketones via Mitsunobu­ Reaction

Abstract

A general method for converting aryl or alkyl methyl ketones to vinylhydrazinedicarboxylates via the Mitsunobu reaction is reported. Unsymmetrical alkyl ketones show high regioselectivity.

tributylphosphine - triphenylphosphine - dimethyl azodicarboxylate - vinylhydrazinedicarboxylates - Mitsunobu reaction

References

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Crystallographic data have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication (CCDC 200312).