Synlett 2003(8): 1186-1188
DOI: 10.1055/s-2003-39892
© Georg Thieme Verlag Stuttgart ˙ New York

Total Synthesis of the Phytotoxic Agent Herbarumin II Using Butane Diacetals of Glycolic Acid as Building Blocks

Elena Diez, Darren J. Dixon, Steven V. Ley*, Alessandra Polara, Felix Rodriguez
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
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Further Information

Publication History

Received 9 April 2003
Publication Date:
11 June 2003 (online)


The total synthesis of the phytotoxic agent herbarumin II has provided an ideal stage to exploit the utility of butane diacetal (BDA) desymmetrised glycolic acid as a primary building block.