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Synlett 2003(6): 0833-0836
DOI: 10.1055/s-2003-38740
DOI: 10.1055/s-2003-38740
LETTER
© Georg Thieme Verlag Stuttgart ˙ New YorkIridium-HetPHOX Complexes for the Catalytic Asymmetric Hydrogenation of Olefins and Imines
Further Information
Received
19 February 2003
Publication Date:
17 April 2003 (online)
Publication History
Publication Date:
17 April 2003 (online)
Abstract
Heterocyclic phosphino oxazolines derived from thiophene and benzo[b]thiophene (HetPHOX) form highly active iridium complexes for the enantioselective hydrogenation of olefins and imines.
Key words
hydrogenation - asymmetric catalysis - ligands - iridium - alkenes
- 1
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reactions:
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Busacca C. inventors; Patent Application, WO 01/18012. (Boehringer Ingelheim Pharmaceuticals)
References
Single crystals of complex 6c were obtained by layering a chloroform solution with pentane. Crystallographic data have been deposited under CCDC 203958.
9Smidt, S. P.; Mukherjee, P.; Pfaltz, A.; Neuburger, M., unpublished results.