Facile Solid-Phase Synthesis of the WAGV-Tetrapeptide Front of the Cyclopeptides Segetalin A and B Terminated by Catechol Moieties and Formation of a Metalla-cyclopeptide

Markus Albrecht; Patrick Stortz; Patrick Weis

doi:10.1055/s-2003-38739

LETTER

Facile Solid-Phase Synthesis of the WAGV-Tetrapeptide Front of the Cyclopeptides Segetalin A and B Terminated by Catechol Moieties and Formation of a Metalla-cyclopeptide

Markus Albrecht*^a, Patrick Stortz^a, Patrick Weis^b
^a Institut für Organische Chemie, RWTH-Aachen, Prof.-Pirlet-Str. 1, 52074 Aachen, Germany
Fax: +49(241)8092385; e-Mail: markus.albrecht@oc.rwth-aachen.de;
^b Institut für Physikalische Chemie, Universität Karlsruhe, Fritz-Haber-Weg, 76128 Karlsruhe, Germany

Abstract

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Abstract

A WAGV-bridged dicatechol ligand is prepared by solid phase synthesis and is used to form a metalla-cyclopeptide, which contains the bioactive part of the naturally occurring segetalins A and B.

Key words

solid-phase - coupling - peptide - ligands - complexes

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References

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