Synthesis of Macrocyclic Polyether-Diester Compounds Using Al₂O₃/MeSO₃H (AMA) as a New Reagent

Abstract

A new simple and convenient method for the synthesis of macrocyclic polyether-diester compounds containing pyridine and phenyl subcyclic units is developed. Various diacids, are selectively esterified in excellent yields by reaction with oligoethylene glycols in the presence of Al₂O₃/MeSO₃H (AMA) as a new reagent without use of any solvents.

Key word

macrocyclic polyether-diester - diacids - oligoethylene glycols - alumina - methanesulfonic acid

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