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Synthesis 2003(4): 0497-0500
DOI: 10.1055/s-2003-37645
PAPER
© Georg Thieme Verlag Stuttgart · New York

A Facile Synthesis of Indolo[2,3-a]pyrrolo[3,4-c]carbazoles via Oxidative Photocyclization of Bisindolylmaleimides

G. Mahesh Reddy, Shyh-Yeon Chen, Biing-Jiun Uang*
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 300, Republic of China
Fax: +886(3)5711082; e-Mail: bjuang@mx.nthu.edu.tw;
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Publikationsverlauf

Received 31 October 2002
Publikationsdatum:
07. März 2003 (online)

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Abstract

A simple and inexpensive oxidative photocyclization of the bisindolylmaleimides in the presence of a catalytic amount of iodine leading to indolo[2,3-a]pyrrolo[3,4-c]carbazoles in 84-90% yields is described.

Key words

photooxidation - indole alkaloid - heterocycle - staurosporine - aglycon

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