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Dtsch Med Wochenschr 2002; 127(8): 384-389
DOI: 10.1055/s-2002-20221
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© Georg Thieme Verlag Stuttgart · New York

Morbus Sudeck - Pathophysiologie und Therapie eines komplexen Schmerzsyndroms

Sudeck`s atrophy: pathophysiology and treatment of a complex pain syndrome M. Weber1 , B. Neundörfer1 , F. Birklein2
  • 1Neurologische Klinik (Direktor: Prof. Dr. B. Neundörfer), Friedrich-Alexander-Universität Erlangen
  • 2Neurologische Universitätsklinik Mainz
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Publikationsverlauf

Manuskript-Eingang: 25. Juli 2001

Annahme nach Revision: 14. Januar 2002

Publikationsdatum:
21. Februar 2002 (online)

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Zusammenfassung: Der "Morbus Sudeck", heute Komplexes Regionales Schmerzsyndrom (CRPS) genannt, ist gekennzeichnet durch eine Symptomentrias motorischer, sensibler und autonomer Störungen. Seine klinische Symptomatik ist charakterisiert durch Spontanschmerz und Hyperalgesie, die nicht auf ein Nervenversorgungsgebiet beschränkt bleiben und dem auslösenden Ereignis nicht angemessen sind. Die Pathophysiologie dieser Erkrankung ist noch immer nicht endgültig geklärt, der Großteil therapeutischer Möglichkeiten ist noch immer rein symptomatisch. Der momentane Stand der Forschung zum CRPS ermöglicht jedoch bereits mehr Einblicke in die Grundlagen der Krankheit als noch vor wenigen Jahren und ermöglicht auch Anfänge einer pathophysiologisch orientierten Therapie.

Sudeck`s atrophy: pathophysiology and treatment of a complex pain syndrome

Summary: The "Morbus Sudeck" or Complex Regional Pain Syndrome (CRPS) forms a typical triad of motor, sensory and autonomic symptoms. It is clinically characterized by spontaneous pain and hyperalgesia not limited to a single nerve territory and disproportionate to the inciting event. An underlying pathophysiology which could explain the whole symptomatology of CRPS is still unknown. Therefore, nowadays therapy is still symptomatic. However, recent research led to a better understanding of the disease and to the beginning of a pathophysiologically orientated therapy.

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Korrespondenz

Dr. Margarete Weber

Neurologische Klinik

Schwabachanlage 6

91054 Erlangen

Telefon: 09131/8533001

Fax: 09131/8534436

eMail: margarete.weber@neuro.med.uni-erlangen.de