A One-Pot Synthesis of Hindered 2,3-Diarylbenzo[b]thiophenes via Suzuki Reaction

Arnault Heynderickx; André Samat; Robert Guglielmetti

doi:10.1055/s-2002-19808

PAPER

A One-Pot Synthesis of Hindered 2,3-Diarylbenzo[b]thiophenes via Suzuki Reaction

Arnault Heynderickx, André Samat*, Robert Guglielmetti
Université de la Méditerranée, Faculté des Sciences de Luminy, UMR 6114 CNRS Case 901, 13288 Marseille Cedex 9, France
Fax: +33(4)91829301; e-Mail: samat@luminy.univ-mrs.fr;

Abstract

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Abstract

Palladium-catalysed cross-coupling of 2,3-dibromobenzo[b]thiophene with phenylboronic acids bearing two ortho substi-tuents have been developed and used for the synthesis of sterically hindered 2,3-diarylbenzo[b]thiophenes.

Key words

Suzuki cross-coupling reaction - palladium - steric hindrance - regioselectivity - 2,3-diarylbenzo[b]thiophenes

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References

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